Membrane lipids and maximum lifespan in clownfish.

Autor: Almaida-Pagan PF; Chronobiology Lab, Department of Physiology, Faculty of Biology, University of Murcia, Mare Nostrum Campus, IUIE, IMIB-Arrixaca, 30100, Murcia, Spain. pfalmaida@um.es.; Ciber Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain. pfalmaida@um.es., Lucas-Sanchez A; Chronobiology Lab, Department of Physiology, Faculty of Biology, University of Murcia, Mare Nostrum Campus, IUIE, IMIB-Arrixaca, 30100, Murcia, Spain.; Ciber Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Martinez-Nicolas A; Chronobiology Lab, Department of Physiology, Faculty of Biology, University of Murcia, Mare Nostrum Campus, IUIE, IMIB-Arrixaca, 30100, Murcia, Spain.; Ciber Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Terzibasi E; Stazione Zoologica Anton Dohrn, Naples, Campania, Italy., de Lama MAR; Chronobiology Lab, Department of Physiology, Faculty of Biology, University of Murcia, Mare Nostrum Campus, IUIE, IMIB-Arrixaca, 30100, Murcia, Spain.; Ciber Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Cellerino A; Department of Neurosciences, Bio@SNS, Scuola Normale Superiore, Pisa, Italy., Mendiola P; Chronobiology Lab, Department of Physiology, Faculty of Biology, University of Murcia, Mare Nostrum Campus, IUIE, IMIB-Arrixaca, 30100, Murcia, Spain.; Ciber Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., de Costa J; Chronobiology Lab, Department of Physiology, Faculty of Biology, University of Murcia, Mare Nostrum Campus, IUIE, IMIB-Arrixaca, 30100, Murcia, Spain.; Ciber Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.
Jazyk: angličtina
Zdroj: Fish physiology and biochemistry [Fish Physiol Biochem] 2022 Feb; Vol. 48 (1), pp. 53-65. Date of Electronic Publication: 2021 Dec 04.
DOI: 10.1007/s10695-021-01037-1
Abstrakt: The longevity-homeoviscous adaptation (LHA) theory of ageing states that lipid composition of cell membranes is linked to metabolic rate and lifespan, which has been widely shown in mammals and birds but not sufficiently in fish. In this study, two species of the genus Amphiprion (Amphiprion percula and Amphiprion clarkii, with estimated maximum lifespan potentials [MLSP] of 30 and 9-16 years, respectively) and the damselfish Chromis viridis (estimated MLSP of 1-2 years) were chosen to test the LHA theory of ageing in a potential model of exceptional longevity. Brain, livers and samples of skeletal muscle were collected for lipid analyses and integral part in the computation of membrane peroxidation indexes (PIn) from phospholipid (PL) fractions and PL fatty acid composition. When only the two Amphiprion species were compared, results pointed to the existence of a negative correlation between membrane PIn value and maximum lifespan, well in line with the predictions from the LHA theory of ageing. Nevertheless, contradictory data were obtained when the two Amphiprion species were compared to the shorter-lived C. viridis. These results along with those obtained in previous studies on fish denote that the magnitude (and sometimes the direction) of the differences observed in membrane lipid composition and peroxidation index with MLSP cannot explain alone the diversity in longevity found among fishes.
(© 2021. The Author(s).)
Databáze: MEDLINE
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