Mixed-methods, descriptive and observational cohort study examining feeding and growth patterns among low birthweight infants in India, Malawi and Tanzania: the LIFE study protocol.

Autor:	Vesel L; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA lvesel@ariadnelabs.org., Spigel L; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Behera JN; Department of Paediatrics, SCB Medical College and Hospital, Cuttack, Orissa, India., Bellad RM; Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India., Das L; Department of Paediatrics, SCB Medical College and Hospital, Cuttack, Orissa, India., Dhaded S; Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India., Goudar SS; Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India., Guruprasad G; Department of Neonatology, JJM Medical College, Davangere, Karnataka, India., Misra S; Department of Paediatrics, SCB Medical College and Hospital, Cuttack, Orissa, India., Panda S; Department of Obstetrics and Gynaecology, City Hospital, Cuttack, Orissa, India., Shamanur LG; Department of Paediatrics, SS Institute of Medical Sciences and Research Center, Davangere, Karnataka, India., Vernekar SS; Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India., Hoffman IF; Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA., Mvalo T; Department of Pediatrics, University of North Carolina Project Malawi, Lilongwe, Malawi.; Department of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA., Phiri M; Department of Pediatrics, University of North Carolina Project Malawi, Lilongwe, Malawi., Saidi F; Department of Pediatrics, University of North Carolina Project Malawi, Lilongwe, Malawi., Kisenge R; Department of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Manji K; Department of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Salim N; Department of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Somji S; Department of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Sudfeld CR; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Adair L; Department of Nutrition, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, North Carolina, USA., Caruso BA; Hubert Department of Global Health, Emory University School of Public Health, Atlanta, Georgia, USA., Duggan C; Center for Nutrition, Boston Children's Hospital, Boston, Massachusetts, USA., Israel-Ballard K; Maternal, Newborn, Child Health and Nutrition Program, PATH, Seattle, Washington, USA., Lee AC; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Martin SL; Department of Nutrition, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, North Carolina, USA., Mansen KL; Maternal, Newborn, Child Health and Nutrition Program, PATH, Seattle, Washington, USA., North K; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Young M; Hubert Department of Global Health, Emory University School of Public Health, Atlanta, Georgia, USA., Benotti E; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Marx Delaney M; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Fishman E; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Fleming K; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Henrich N; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Miller K; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Subramanian L; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Tuller DE; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA., Semrau KE; Ariadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Jazyk:	angličtina
Zdroj:	BMJ open [BMJ Open] 2021 Dec 02; Vol. 11 (12), pp. e048216. Date of Electronic Publication: 2021 Dec 02.
DOI:	10.1136/bmjopen-2020-048216
Abstrakt:	Introduction: Ending preventable deaths of newborns and children under 5 will not be possible without evidence-based strategies addressing the health and care of low birthweight (LBW, <2.5 kg) infants. The majority of LBW infants are born in low- and middle-income countries (LMICs) and account for more than 60%-80% of newborn deaths. Feeding promotion tailored to meet the nutritional needs of LBW infants in LMICs may serve a crucial role in curbing newborn mortality rates and promoting growth. The Low Birthweight Infant Feeding Exploration (LIFE) study aims to establish foundational knowledge regarding optimal feeding options for LBW infants in low-resource settings throughout infancy. Methods and Analysis: LIFE is a formative, multisite, observational cohort study involving 12 study facilities in India, Malawi and Tanzania, and using a convergent parallel, mixed-methods design. We assess feeding patterns, growth indicators, morbidity, mortality, child development and health system inputs that facilitate or hinder care and survival of LBW infants. Ethics and Dissemination: This study was approved by 11 ethics committees in India, Malawi, Tanzania and the USA. The results will be disseminated through peer-reviewed publications and presentations targeting the global and local research, clinical, programme implementation and policy communities. Trial Registration Numbers: NCT04002908 and CTRI/2019/02/017475. Competing Interests: Competing interests: All authors completed the ICMJE conflict of interest form and were funded by the Bill & Melinda Gates Foundation for this work as part of the LIFE study. ACCL, BAC, CRS, DET, KEAS, KI-B, KLM, KMa, MMD, RK and SS have received funding from the Bill & Melinda Gates Foundation for maternal and newborn health work at large. CD reports other from American Society for Nutrition, other from UpToDate and other from People’s Medical Publishing House outside the submitted work. ACCL reports grants from the WHO and National Institute of Health NICHD outside the submitted work. (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu