Efficacy of an iodoform-based filling material for pulpectomy of primary teeth: A 24-month non-inferiority randomized clinical trial.

Autor: Bresolin CR; Department of Pediatric Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil.; Faculdades Metropolitanas Unidas, School of Dentistry, São Paulo, SP, Brazil., Marques RPS; Department of Pediatric Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil., Okamura B; Department of Pediatric Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil., Costa C; Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil., Moura-Netto C; Faculty Dental Medicine, Center for Interdisciplinary Research in Health-SalivaTec Lab, Universidade Católica Portuguesa, Viseu, Portugal., Lara JS; Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University School of Dentistry, Indianapolis, Indiana, USA., Mello-Moura ACV; Faculty Dental Medicine, Center for Interdisciplinary Research in Health-SalivaTec Lab, Universidade Católica Portuguesa, Viseu, Portugal., Mendes FM; Department of Pediatric Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: International journal of paediatric dentistry [Int J Paediatr Dent] 2022 Sep; Vol. 32 (5), pp. 668-677. Date of Electronic Publication: 2022 Apr 08.
DOI: 10.1111/ipd.12945
Abstrakt: Aim: The aim of this non-inferiority randomized clinical trial was to compare the efficacy of an iodoform-based paste (Guedes-Pinto -(GP)) as a filling material in pulpectomies of primary teeth, and a standard material composed by calcium hydroxide and iodoform (CaOH/Iodof paste; Vitapex ® ).
Design: A total of 104 teeth from 61 children (3-8 years old) were randomly allocated to two groups according to filling materials. Children were followed up for 24 months. The primary endpoint was the treatment success rate evaluated through clinical and radiographic examinations at follow-up, and the secondary outcome was the analysis of the canal filling quality. Differences in the proportion of treatment success was calculated based on 95% confidence intervals (95% CI) and with the Miettinen and Nurminen method in the intention-to-treat population, considering a -20% of the non-inferiority limit.
Results: From 104 randomized teeth, 102 were followed up after 24 months (attrition rate of 1.9%). The success rate of teeth treated with the GP paste was 86.8% (95% CI: 69.9-94.9) and 78.4% (95% CI: 61.8-89.1) with the CaOH/Iodof paste. Consequently, a non-inferiority of the GP paste was observed when compared to the CaOH/Iodof paste (P < .001).
Conclusion: The GP paste has a non-inferior success rate than the CaOH/Iodof paste used as filling material for pulpectomy in primary teeth.
(© 2021 BSPD, IAPD and John Wiley & Sons Ltd.)
Databáze: MEDLINE
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