Improved separation scheme for 44 Sc produced by irradiation of nat Ca targets with 12.8 MeV protons.
Autor: | Kurakina ES; Dzhelepov Laboratory of Nuclear Problems, Joint Institute for Nuclear Research, Dubna 141980, Russian Federation; Department of High-Energy Chemistry and Radioecology, D. Mendeleev University of Chemical Technology of Russia, Moscow 125047, Russian Federation; Life Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, British Columbia V6T 2A3, Canada., Wharton L; Life Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, British Columbia V6T 2A3, Canada; Medicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada., Hoehr C; Life Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, British Columbia V6T 2A3, Canada; Department of Physics and Astronomy, University of Victoria, Victoria, British Columbia V8W 2Y2, Canada; Department of Computer Science, Mathematics, Physics, and Statistics, University of British Columbia Okanagan, Kelowna, British Columbia V1V 1V7, Canada., Orvig C; Medicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada., Magomedbekov EP; Department of High-Energy Chemistry and Radioecology, D. Mendeleev University of Chemical Technology of Russia, Moscow 125047, Russian Federation., Filosofov D; Dzhelepov Laboratory of Nuclear Problems, Joint Institute for Nuclear Research, Dubna 141980, Russian Federation., Radchenko V; Life Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, British Columbia V6T 2A3, Canada; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada. Electronic address: vradchenko@triumf.ca. |
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Jazyk: | angličtina |
Zdroj: | Nuclear medicine and biology [Nucl Med Biol] 2022 Jan-Feb; Vol. 104-105, pp. 22-27. Date of Electronic Publication: 2021 Nov 11. |
DOI: | 10.1016/j.nucmedbio.2021.11.002 |
Abstrakt: | Introduction: 44 Sc is of great interest as a positron emission tomography (PET) radionuclide due to its suitable nuclear characteristics: E Methods: The irradiation was performed at TRIUMF using the 13 MeV cyclotron. The separation consisted of a combination of DGA branched resin and Dowex 50Wx8 (200-400 mesh). The distribution coefficients of Sc 3+ on Dowex 50Wx8 (NH Results and Conclusion: The tested scheme allows both a reliable separation of 44 Sc from the target material as well as from the other competitive metals and a final fraction with high specific activity. The achieved radiochemical yield was 95 ± 3%. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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