COVID-19 vaccinations: The unknowns, challenges, and hopes.

Autor: Mohamed K; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Universal Scientific Education and Research Network (USERN), Manama, Bahrain., Rzymski P; Department of Environmental Medicine, Poznań University of Medical Sciences, Poznań, Poland.; Universal Scientific Education and Research Network (USERN), Poznań, Poland., Islam MS; Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Universal Scientific Education and Research Network (USERN), Dhaka, Bangladesh., Makuku R; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Universal Scientific Education and Research Network (USERN), Harare, Zimbabwe., Mushtaq A; International Higher School of Medicine, International University of Kyrgyzstan, Bishkek, Kyrgyzstan.; Universal Scientific Education and Research Network (USERN), Bishkek, Kyrgyzstan., Khan A; Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.; Universal Scientific Education and Research Network (USERN), Islamabad, Pakistan., Ivanovska M; Department of Microbiology and Immunology, Research Center, Medical University, Plovdiv, Bulgaria.; Universal Scientific Education and Research Network (USERN), Plovdiv, Bulgaria., Makka SA; Neuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.; Universal Scientific Education and Research Network (USERN), Beirut, Lebanon., Hashem F; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Universal Scientific Education and Research Network (USERN), Manama, Bahrain., Marquez L; College of Social Sciences and Philosophy, University of the Philippines Diliman, Quezon City, Philippines.; Universal Scientific Education and Research Network (USERN), Quezon City, Philippines., Cseprekal O; Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary.; Universal Scientific Education and Research Network (USERN), Budapest, Hungary., Filgueiras IS; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; Universal Scientific Education and Research Network (USERN), São Paulo, Brazil., Fonseca DLM; Universal Scientific Education and Research Network (USERN), São Paulo, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Mickael E; Department of Rheumatology and Physical Medicine, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.; Universal Scientific Education and Research Network (USERN), Yaoundé, Cameroon., Ling I; School of Science, Monash University Malasia, Jalan Lagoon Selatan, Darul Ehsan, Selangor, Malaysia.; Universal Scientific Education and Research Network (USERN), Darul Ehsan, Selangor, Malaysia., Arero AG; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Universal Scientific Education and Research Network (USERN), Addis Ababa, Ethiopia., Cuschieri S; Faculty of Medicine and Surgery, University of Malta, Msida, Malta.; Universal Scientific Education and Research Network (USERN), Valletta, Malta., Minakova K; National Technical University 'Kharkiv Polytechnic Institute', Kharkiv, Ukraine.; Universal Scientific Education and Research Network (USERN), Kyiv, Ukraine., Rodríguez-Román E; Center for Microbiology and Cell Biology, Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela.; Universal Scientific Education and Research Network (USERN), Caracas, Venezuela., Abarikwu SO; Department of Biochemistry, University of Port Harcourt, Choba, Nigeria.; Universal Scientific Education and Research Network (USERN), Choba, Nigeria., Faten AB; Tunisia Polytechnic School, University of Carthage, Tunis, Tunisia.; Universal Scientific Education and Research Network (USERN), Tunis, Tunisia., Grancini G; Department of Chemistry, Physical Chemistry Unit, University of Pavia, Pavia, Italy.; Universal Scientific Education and Research Network (USERN), Pavia, Italy., Cabral-Marques O; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; Universal Scientific Education and Research Network (USERN), São Paulo, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Rezaei N; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Jazyk: angličtina
Zdroj: Journal of medical virology [J Med Virol] 2022 Apr; Vol. 94 (4), pp. 1336-1349. Date of Electronic Publication: 2021 Dec 10.
DOI: 10.1002/jmv.27487
Abstrakt: The entire world has been suffering from the coronavirus disease 2019 (COVID-19) pandemic since March 11, 2020. More than a year later, the COVID-19 vaccination brought hope to control this viral pandemic. Here, we review the unknowns of the COVID-19 vaccination, such as its longevity, asymptomatic spread, long-term side effects, and its efficacy on immunocompromised patients. In addition, we discuss challenges associated with the COVID-19 vaccination, such as the global access and distribution of vaccine doses, adherence to hygiene guidelines after vaccination, the emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, and vaccine resistance. Despite all these challenges and the fact that the end of the COVID-19 pandemic is still unclear, vaccines have brought great hope for the world, with several reports indicating a significant decline in the risk of COVID19-related infection and hospitalizations.
(© 2021 Wiley Periodicals LLC.)
Databáze: MEDLINE
Externí odkaz: