Anti-Vel alloimmunization and severe hemolytic disease of the fetus and newborn.

Autor:	Moise KJ Jr; Department of Obstetrics, Gynecology, and Reproductive Sciences , The McGovern School of Medicine at the University of Texas Health Science Center, and the Fetal Center at Children's Memorial Hermann Hospital , Suite 700 , 6410 Fannin Street , Houston, TX 77030., Morales Y; Department of Obstetrics, Gynecology, and Reproductive Sciences , The McGovern School of Medicine at the University of Texas Health Science Center, and the Fetal Center at Children's Memorial Hermann Hospital , Houston, TX., Bertholf MF; Gulf Coast Regional Blood Center , Houston, TX., Rossmann SN; Gulf Coast Regional Blood Center , Houston, TX., Bai Y; The Department of Pathology and Laboratory Medicine , The McGovern School of Medicine at the University of Texas Health Science Center , Houston, TX.
Jazyk:	angličtina
Zdroj:	Immunohematology [Immunohematology] 2019; Vol. 33 (4), pp. 152-154.
DOI:	10.21307/immunohematology-2019-021
Abstrakt:	Only rare cases of anti-Vel-associated mild-to-moderate hemolytic disease of the fetus and newborn have been previously reported. No case of fetal anemia requiring prenatal therapy has been noted to date. We report such a case recently encountered at our Fetal Center. Strategies are discussed for managing pregnancy complicated with alloimmunization to an antibody to a high-prevalence antigen, including sources of red blood cells for intrauterine transfusions. Only rare cases of anti-Vel–associated mild-to-moderate hemolytic disease of the fetus and newborn have been previously reported. No case of fetal anemia requiring prenatal therapy has been noted to date. We report such a case recently encountered at our Fetal Center. Strategies are discussed for managing pregnancy complicated with alloimmunization to an antibody to a high-prevalence antigen, including sources of red blood cells for intrauterine transfusions.
Databáze:	MEDLINE
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