Cross-sectional comparison of office and ambulatory pulse wave velocity by two methods, and their changes after lifestyle or medical interventions in hypertension.

Autor:	Batta D; Department of Family Medicine., Körösi B; Department of Family Medicine., Gyöngyösi H; Department of Family Medicine., Nemcsik-Bencze Z; Department of Radiology, Medical Imaging Center, Semmelweis University, Budapest, Hungary., László A; GP practice Jula/Schindler, Nuremberg, Germany., Tislér A; Department of Internal Medicine and Oncology., Cseprekál O; Department of Transplantation and Surgery, Semmelweis University., Nemcsik J; Department of Family Medicine.; Health Service of Zugló (ZESZ), Budapest, Hungary.
Jazyk:	angličtina
Zdroj:	Journal of hypertension [J Hypertens] 2022 Mar 01; Vol. 40 (3), pp. 470-477.
DOI:	10.1097/HJH.0000000000003036
Abstrakt:	Objective: Pulse wave velocity (PWV), the most accepted biomarker of arterial stiffening can be measured by different methods and in the past decade, its 24 h monitoring has also become available. The aim of our study was to compare office and ambulatory PWVs and in a proportion of patients to compare the changes of PWVs after the initiation of lifestyle modifications or antihypertensive medication. Methods: Office carotid-femoral PWV was measured with the tonometric PulsePen device (PP PWV), first hour and 24 h ambulatory oscillometric PWVs were evaluated with Mobil-O-Graph (MOB first hour PWV and MOB 24 h PWV, respectively). In new hypertensive patients, the measurements were repeated 3 months after the initiation of antihypertensive medication. In white-coat hypertensive patients after lifestyle modifications the measurements were repeated at 12 months. Results: One hundred and five participants were involved with 22 new hypertensive and 22 white-coat hypertensive (WhHT) patients. PP PWV [8.7 (7.3-9.9) m/s] differed from MOB first hour PWV [7.3 (6.5-8.8) m/s] and MOB 24 h PWV [7.4 (6.4-8.8) m/s] as well (P < 0.05). PP PWV significantly decreased both in hypertensive [by 0.9 (0.4-1.5) m/s, P < 0.05] and WhHT patients [by 0.3 (-0.1 to 1) m/s, P < 0.05]. MOB first hour PWV did not change neither in hypertensive patients, nor in WhHT patients. MOB 24 h PWV decreased only in hypertensive patients [by 0.2 (0-0.6) m/s], which was less pronounced compared with PP PWV (P < 0.05). Conclusion: The significant differences observed both in the cross-sectional and in the prospective parts of our study suggests that the two methods are not interchangeable. (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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