Graphene Quantum Dots and Cu(I) Liquid Crystal for Advanced Electrochemical Detection of Doxorubicine in Aqueous Solutions.

Autor:	Motoc Ilies S; 'Coriolan Drăgulescu' Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, Romania., Schinteie B; 'Coriolan Drăgulescu' Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, Romania., Pop A; Department of Applied Chemistry and Engineering of Inorganic Compounds and Environment, Politehnica University of Timisoara, 2 Victoriei Square, 300006 Timisoara, Romania., Negrea S; National Institute of Research and Development for Industrial Ecology (INCD ECOIND), Timisoara Branch, 300431 Timisoara, Romania.; Department of Environmental Engineering and Management, 'Gheorghe Asachi' Technical University of Iasi, 700050 Iasi, Romania., Cretu C; 'Coriolan Drăgulescu' Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, Romania., Szerb EI; 'Coriolan Drăgulescu' Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, Romania., Manea F; Department of Applied Chemistry and Engineering of Inorganic Compounds and Environment, Politehnica University of Timisoara, 2 Victoriei Square, 300006 Timisoara, Romania.
Jazyk:	angličtina
Zdroj:	Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2021 Oct 21; Vol. 11 (11). Date of Electronic Publication: 2021 Oct 21.
DOI:	10.3390/nano11112788
Abstrakt:	Two paste electrodes based on graphene quantum dots and carbon nanotubes (GRQD/CNT) and one modified with a homoleptic liquid crystalline Cu(I) based coordination complex (Cu/GRQD/CNT) were obtained and morphostructurally and electrochemically characterized in comparison with simple CNT electrode (CNT) for doxorubicine (DOX) detection in aqueous solutions. GRQD/CNT showed the best electroanalytical performance by differential pulse voltammetry technique (DPV). Moreover, applying a preconcentration step prior to detection stage, the lowest limit of detection (1 ng/L) and the highest sensitivity (216,105 µA/mg·L -1 ) in comparison with reported literature data were obtained. Cu/GRQD/CNT showed good results using multiple pulse amperometry technique (MPA) and a favorable shifting of the potential detection to mitigate potential interferences. Both GRQD-based paste electrodes have a great potential for practical utility in DOX determination in water at trace concentration levels, using GRQD/CNT with DPV and in pharmaceuticals formulations using Cu/GRQD/CNT with MPA.
Databáze:	MEDLINE
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