A Review of Rhazya stricta Decne Phytochemistry, Bioactivities, Pharmacological Activities, Toxicity, and Folkloric Medicinal Uses.

Autor: Albeshri A; Department of Biological Science, Faculty of Science, King Abdul-Aziz University, Jeddah 21589, Saudi Arabia., Baeshen NA; Department of Biological Science, Faculty of Science, King Abdul-Aziz University, Jeddah 21589, Saudi Arabia., Bouback TA; Department of Biological Science, Faculty of Science, King Abdul-Aziz University, Jeddah 21589, Saudi Arabia.; Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology, King Abdul-Aziz University, Jeddah 21589, Saudi Arabia., Aljaddawi AA; Department of Biological Science, Faculty of Science, King Abdul-Aziz University, Jeddah 21589, Saudi Arabia.
Jazyk: angličtina
Zdroj: Plants (Basel, Switzerland) [Plants (Basel)] 2021 Nov 19; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 19.
DOI: 10.3390/plants10112508
Abstrakt: The local medicinal plant Rhazya stricta Decne is reviewed for its folkloric medicinal, phytochemical, pharmacological, biological, and toxicological features. R. stricta has been used widely in different cultures for various medical disorders. The phytochemical studies performed on the R. stricta extract revealed many alkaloidal and fatty acid compounds. Moreover, several flavonoid and terpenoid compounds were also detected. Pharmacological activates of R. stricta extracts are approved to possess antimicrobial, antioxidant, anticancer, antidiabetic, and antihypertensive activities. Additionally, R. stricta extract was found to hold biological activates such as larvicidal and phytoremediation activates R. stricta extract was found to be toxic, genotoxic, and mutagenic. R. stricta contains novel phytochemical compounds that have not been investigated pharmacologically. Further research is needed through in vitro and in vivo experiments to pave the road for these compounds for medical, veterinary, and ecological uses.
Databáze: MEDLINE