Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.

Autor: Valente FX; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Gavara J; Centro de Biomateriales y Ingeniería de Tejidos, Universitat Politècnica de Valencia, 46022 Valencia, Spain., Gutierrez L; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Rios-Navarro C; Instituto de Investigación Sanitaria INCLIVA, 46010 Valencia, Spain., Rello P; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Maymi M; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Fernandez-Galera R; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Monmeneu JV; Unidad de Resonancia Magnética Cardiovascular, Exploraciones Radiológicas Especiales (ERESA), 46015 Valencia, Spain., Sao-Aviles A; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Lopez-Lereu MP; Unidad de Resonancia Magnética Cardiovascular, Exploraciones Radiológicas Especiales (ERESA), 46015 Valencia, Spain., Gonzalez-Alujas MT; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Moratal D; Centro de Biomateriales y Ingeniería de Tejidos, Universitat Politècnica de Valencia, 46022 Valencia, Spain., Cuellar H; Radiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Barrabés J; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Otaegui I; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Evangelista A; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Ferreira I; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain., Bodi V; Instituto de Investigación Sanitaria INCLIVA, 46010 Valencia, Spain.; Cardiology Department, Hospital Clínico Universitario de Valencia, 46010 Valencia, Spain.; Centrode Investigación Biomédica en Red-Cardiovascular (CIBER-CV), 28029 Madrid, Spain.; Medicine Department, Facultad de Medicina y Odontología, Universidad de Valencia, 46010 Valencia, Spain., Rodriguez-Palomares J; Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2021 Nov 12; Vol. 10 (22). Date of Electronic Publication: 2021 Nov 12.
DOI: 10.3390/jcm10225261
Abstrakt: In acute ST-segment elevation myocardial infarction (STEMI) late gadolinium enhancement (LGE) may underestimate segmental functional recovery. We evaluated the predictive value of cardiac magnetic resonance (CMR) feature-tracking (FT) for functional recovery and whether it incremented the value of LGE compared to low-dose dobutamine stress echocardiography (LDDSE) and speckle-tracking echocardiography (STE). Eighty patients underwent LDDSE and CMR within 5-7 days after STEMI and segmental functional recovery was defined as improvement in wall-motion at 6-months CMR. Optimal conventional and FT parameters were analyzed and then also applied to an external validation cohort of 222 STEMI patients. Circumferential strain (CS) was the strongest CMR-FT predictor and addition to LGE increased the overall accuracy to 74% and was especially relevant in segments with 50-74% LGE (AUC 0.60 vs. 0.75, p = 0.001). LDDSE increased the overall accuracy to 71%, and in the 50-74% LGE subgroup improved the AUC from 0.60 to 0.69 ( p = 0.039). LGE + CS showed similar value as LGE + LDDSE. In the validation cohort, CS was also the strongest CMR-FT predictor of recovery and addition of CS to LGE improved overall accuracy to 73% although this difference was not significant (AUC 0.69, p = 0.44). Conclusion: CS is the strongest CMR-FT predictor of segmental functional recovery after STEMI. Its incremental value to LGE is comparable to that of LDDSE whilst avoiding an inotropic stress agent. CS is especially relevant in segments with 50-74% LGE where accuracy is lower and further testing is frequently required to clarify the potential for recovery.
Databáze: MEDLINE
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