Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature.

Autor: Bellini MI; Azienda Ospedaliera San Camillo Forlanini, 00152 Rome, Italy.; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Biffoni M; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Patrone R; ICTUS, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy., Borcea MC; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Costanzo ML; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Garritano T; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Melcarne R; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Menditto R; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Metere A; General Surgery Department, Ospedale dei Castelli (O.D.C.), Via Nettunense Km 11,5, 00040 Rome, Italy., Scorziello C; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Summa M; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Ventrone L; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., D'Andrea V; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy., Giacomelli L; Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2021 Nov 12; Vol. 10 (22). Date of Electronic Publication: 2021 Nov 12.
DOI: 10.3390/jcm10225258
Abstrakt: There is controversy in the literature regarding a distinct subset of thyroid carcinoma whose histologically classification falls between well-differentiated and anaplastic carcinomas, previously identified as 'poorly differentiated thyroid carcinoma' (PDTC), or 'insular carcinoma', in view of the peculiar morphological characteristics of the cell groupings. The correct diagnosis and treatment of this entity have important prognostic and therapeutic significance. In this review, we describe the epidemiology, diagnosis, and management of PDTC and report our single centre experience to add to the limited evidence existing in the literature.
Databáze: MEDLINE
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