Biosynthesized Gold Nanoparticles Integrated Ointment Base for Repellent Activity Against Aedes aegypti L.

Autor: Sundararajan B; College of Horticulture and Landscape Architecture, Southwest University, Chongqing, People's Republic of China. sundarpbt87@gmail.com., Sathishkumar G; School of Materials and Energy, Southwest University, Chongqing, People's Republic of China., Seetharaman PK; Dept of Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India., Moola AK; Dept of Biotechnology, Aditya Degree and PG College, Kakinada, Andhra Pradesh, India., Duraisamy SM; Dept of Botany, Arignar Anna Govt Arts College, Musiri, Tiruchirappalli, Tamil Nadu, India., Mutayran AASB; College of Pharmacy (Girls), Prince Sattam Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia., Seshadri VD; College of Pharmacy (Girls), Prince Sattam Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia., Thomas A; School of Pharmacy, Catholic University of Health and Allied Sciences, Mwanza, Tanzania., Ranjitha Kumari BD; Dept of Botany, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India., Sivaramakrishnan S; Dept of Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India., Kweka EJ; Division of Livestock and Human Diseases Vector Control, Mosquito Section, Tropical Pesticides Research Institute, Arusha, Tanzania.; Dept of Medical Parasitology and Entomology, School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania., Zhou Z; College of Horticulture and Landscape Architecture, Southwest University, Chongqing, People's Republic of China. zhouzhiqin@swu.edu.cn.
Jazyk: angličtina
Zdroj: Neotropical entomology [Neotrop Entomol] 2022 Feb; Vol. 51 (1), pp. 151-159. Date of Electronic Publication: 2021 Nov 25.
DOI: 10.1007/s13744-021-00920-z
Abstrakt: The present study focused on preparing a nano-ointment base integrated with biogenic gold nanoparticles from Artemisia vulgaris L. leaf extract. As prepared, nano-ointment was characterized by using Fourier-transform infrared spectroscopy, and the morphology of the nano-ointment was confirmed through a scanning electron microscope. Initially, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide results showed nano-ointment cytocompatibility at different concentrations (20-200 μg/mL) against L929 cells. The in vitro hemolysis assay also revealed that the nano-ointment is biocompatible. Further studies confirmed that nano-ointment has repellent activity with various concentrations (12.5, 25, 50, 75, and 100 ppm). At 100 ppm concentration, the highest repellent activity was observed at 60-min protection time against the Aedes aegypti L. female mosquitoes. The results indicated that the increasing concentration of nano-ointment prolongs the protection time. Moreover, the outcome of this study provides an alternative nano-ointment to synthetic repellent and insecticides after successful clinical trials. It could be an eco-friendly, safer nano-bio repellent, which can protect from dengue fever mosquitoes.
(© 2021. Sociedade Entomológica do Brasil.)
Databáze: MEDLINE
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