| Autor: |
Ion A; 1st Medical Department, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sf. Spiridon', 700111 Iasi, Romania., Stafie C; Department of Preventive Medicine and Interdisciplinarity, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania., Mitu O; 1st Medical Department, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sf. Spiridon', 700111 Iasi, Romania., Ciobanu CE; Cardiology Clinic, Clinical Emergency Hospital 'Sf. Spiridon', 700111 Iasi, Romania., Halitchi DI; 1st Medical Department, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania., Costache AD; 1st Medical Department, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania., Bobric C; Neurology Clinic, Clinical Rehabilitation Hospital, 700661 Iasi, Romania., Troase R; Neurology Clinic, Clinical Rehabilitation Hospital, 700661 Iasi, Romania., Mitu I; Department of Morpho-Functional Sciences II, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania., Huzum B; Department of Physiology, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania., Duca ST; 1st Medical Department, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sf. Spiridon', 700111 Iasi, Romania., Costache II; 1st Medical Department, University of Medicine and Pharmacy 'Grigore T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sf. Spiridon', 700111 Iasi, Romania. |
| Abstrakt: |
Biomarkers are important diagnostic and prognostic tools as they provide results in a short time while still being an inexpensive, reproducible and accessible method. Their well-known benefits have placed them at the forefront of research in recent years, with new and innovative discoveries being implemented. Cardiovascular and neurological diseases often share common risk factors and pathological pathways which may play an important role in the use and interpretation of biomarkers' values. Among the biomarkers used extensively in clinical practice in cardiology, hs-TroponinT, CK-MB and NTproBNP have been shown to be strongly influenced by multiple neurological conditions. Newer ones such as galectin-3, lysophosphatidylcholine, copeptin, sST2, S100B, myeloperoxidase and GDF-15 have been extensively studied in recent years as alternatives with an increased sensitivity for cardiovascular diseases, but also with significant results in the field of neurology. Thus, given their low specificity, the values interpretation must be correlated with the clinical judgment and other available investigations. |
