| Autor: |
Vuong NQ; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Caugiay, Hanoi 10000, Vietnam., Chien VV; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Caugiay, Hanoi 10000, Vietnam., Hue NT; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Caugiay, Hanoi 10000, Vietnam., Hang PT; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Caugiay, Hanoi 10000, Vietnam., Nam NH; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Caugiay, Hanoi 10000, Vietnam., Cuong PV; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Caugiay, Hanoi 10000, Vietnam., Nhiem NX; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Caugiay, Hanoi 10000, Vietnam. |
| Abstrakt: |
One new phenylpropanoid glycoside, myxosmoside I ( 1 ) and six known compounds, arenarioside ( 2 ), verbacoside ( 3 ), 3-formylindole ( 4 ), 5-hydroxymethyl furfural ( 5 ), D-manitol ( 6 ), and glycerol monooleate ( 7 ) were isolated from the roots of Myxopyrum smilacifolium ( Wall .) Blume. Their chemical structures were determined by 1D-, 2D-NMR, and mass spectra, chemical methods, and compared with those reported in the literature. All compounds were evaluated for α -glucosidase inhibitory effect. Among them, phenylpropanoid glycosides 1 - 3 significantly inhibited α -glucosidase activity with IC 50 values of 30.0 ± 0.9, 66.6 ± 2.3, and 36.9 ± 2.0 µM, respectively. |
