Adult pulmonary blastoma in an adult with urothelial cancer: A case report.

Autor:	Kolekar S; Department of Internal Medicine, Zealand University Hospital, Roskilde, Denmark.; Department of Clinical Medicine, University of Copenhagen, Denmark., Gudmundsdottir K; Department of Respiratory Medicine, Naestved Hospital, Naestved, Denmark., Olsen KE; Department of Pathology, Odense University Hospital, Denmark., Sivapalan P; Department of Internal Medicine, Zealand University Hospital, Roskilde, Denmark., Clementsen PF; Copenhagen Academy for Medical Education and Simulation (CAMES), Rigshospitalet, Denmark.; University of Copenhagen and the Capital Region of Denmark, Copenhagen, Denmark., Bodtger U; Department of Internal Medicine, Zealand University Hospital, Roskilde, Denmark.; Department of Respiratory Medicine, Naestved Hospital, Naestved, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
Jazyk:	angličtina
Zdroj:	Respiratory medicine case reports [Respir Med Case Rep] 2021 Nov 10; Vol. 34, pp. 101556. Date of Electronic Publication: 2021 Nov 10 (Print Publication: 2021).
DOI:	10.1016/j.rmcr.2021.101556
Abstrakt:	Pulmonary blastoma is an aggressive lung cancer with incidence ranging from 0.25-0.5 of all the reported lung cancers. Although, pulmonary blastoma is seen commonly in childhood its very rare in adults. Surgical treatment is often the treatment of choice, but benefits of neoadjuvant chemotherapy are unclear. People with DICER1 syndrome commonly develop Pulmonary blastoma and do have concomitant or previous history of benign or malignant tumours in extra pulmonary site like kidney, thyroid, ovary cervix testicle and eye. As per our knowledge, this is the first case of adult pulmonary blastoma previously diagnosed with urothelial cancer and a strong familial predilection of malignancy, with negative genetic test for DICER1 mutations. (© 2021 Published by Elsevier Ltd.)
Databáze:	MEDLINE
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