| Autor: |
Gokhan Alici; Department of Cardiology, Okmeydani Training and Research Hospital, Istanbul, Turkey., Hasan Ali Barman; Department of Cardiology, Institute of Cardiology, Istanbul University - Cerrahpaşa, Istanbul, Turkey., Ramazan Asoglu; Department of Cardiology, Adiyaman Training ve Research Hospital, Adiyaman, Turkey., Atici A; Department of Cardiology, Faculty of Medicine, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey., Akciger AN; Department of Cardiology, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey., Sit O; Department of Cardiology, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey., Dogan O; Department of Cardiology, Institute of Cardiology, Istanbul University - Cerrahpaşa, Istanbul, Turkey., Yucel Yavuz; Department of Anesthesiology and Intensive Care, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey., Songul Borahan; Department of Anesthesiology and Intensive Care, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey., Omer Genc; Department of Cardiology, Agri Training ve Research Hospital, Agri, Turkey., Baris Gungor; Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Training and Research Hospital, Istanbul, Turkey. |
| Abstrakt: |
The aim of this study was to investigate the patient characteristics and laboratory parameters for COVID-19 non-survivors as well as to find risk factors for major bleeding complications. For this retrospective study, the data of patients who died with COVID-19 in our intensive care unit were collected in the period of March 20 - April 30, 2020. D-dimer, platelet count, C-reactive protein (CRP), troponin, and international normalized ratio (INR) levels were recorded on the 1st, 5th, and 10th days of hospitalization in order to investigate the possible correlation of laboratory parameter changes with in-hospital events. A total of 161 non-survivors patients with COVID-19 were included in the study. The median age was 69.8±10.9 years, and 95 (59%) of the population were male. Lung-related complications were the most common in-hospital complications. Patients with COVID-19 had in-hospital complications such as major bleeding (39%), hemoptysis (14%), disseminated intravascular coagulation (13%), liver failure (21%), ARDS (85%), acute kidney injury (40%), and myocardial injury (70%). A multiple logistics regression analysis determined that age, hypertension, diabetes mellitus, use of acetylsalicylic acid (ASA) or low molecular weight heparin (LMWH), hemoglobin, D-dimer, INR, and acute kidney injury were independent predictors of major bleeding. Our results showed that a high proportion of COVID-19 non-survivors suffered from major bleeding complications. |
