Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workers.
Autor: | León-Jiménez A; Pulmonology, Allergy and Thoracic Surgery Department, Puerta del Mar University Hospital, Cádiz, Spain. antonio.leon.sspa@juntadeandalucia.es.; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Cádiz, Spain. antonio.leon.sspa@juntadeandalucia.es., Mánuel JM; IMEYMAT: University Institute of Research in Electron Microscopy and Materials of the University of Cadiz, Puerto Real, Cádiz, Spain.; Department of Condensed Matter Physics, School of Sciences, University of Cádiz, Puerto Real, Cádiz, Spain., García-Rojo M; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Cádiz, Spain.; Department of Anatomic Pathology, Puerta del Mar University Hospital, Cádiz, Spain., Pintado-Herrera MG; INMAR: University Research Institute of Marine Research, University of Cádiz, Puerto Real, Cádiz, Spain.; Department of Physical Chemistry, CASEM, University of Cádiz, Puerto Real, Cádiz, Spain., López-López JA; INMAR: University Research Institute of Marine Research, University of Cádiz, Puerto Real, Cádiz, Spain.; Department of Analytical Chemistry, CASEM, University of Cádiz, Puerto Real, Cádiz, Spain., Hidalgo-Molina A; Pulmonology, Allergy and Thoracic Surgery Department, Puerta del Mar University Hospital, Cádiz, Spain.; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Cádiz, Spain., García R; IMEYMAT: University Institute of Research in Electron Microscopy and Materials of the University of Cadiz, Puerto Real, Cádiz, Spain.; Department of Materials Science, Metallurgical Engineering and Inorganic Chemistry, School of Sciences, University of Cádiz, Puerto Real, Cádiz, Spain., Muriel-Cueto P; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Cádiz, Spain.; Department of Anatomic Pathology, Puerta del Mar University Hospital, Cádiz, Spain., Maira-González N; Department of Anatomic Pathology, Puerto Real University Hospital, Cádiz, Spain., Del Castillo-Otero D; Department of Pulmonology, Puerto Real University Hospital, Cádiz, Spain., Morales FM; IMEYMAT: University Institute of Research in Electron Microscopy and Materials of the University of Cadiz, Puerto Real, Cádiz, Spain.; Department of Materials Science, Metallurgical Engineering and Inorganic Chemistry, School of Sciences, University of Cádiz, Puerto Real, Cádiz, Spain. |
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Jazyk: | angličtina |
Zdroj: | Particle and fibre toxicology [Part Fibre Toxicol] 2021 Nov 22; Vol. 18 (1), pp. 41. Date of Electronic Publication: 2021 Nov 22. |
DOI: | 10.1186/s12989-021-00434-x |
Abstrakt: | Background: Engineered stone silicosis is an emerging disease in many countries worldwide produced by the inhalation of respirable dust of engineered stone. This silicosis has a high incidence among young workers, with a short latency period and greater aggressiveness than silicosis caused by natural materials. Although the silica content is very high and this is the key factor, it has been postulated that other constituents in engineered stones can influence the aggressiveness of the disease. Different samples of engineered stone countertops (fabricated by workers during the years prior to their diagnoses), as well as seven lung samples from exposed patients, were analyzed by multiple techniques. Results: The different countertops were composed of SiO Conclusion: Some of the volatile organic compounds, polycyclic aromatic hydrocarbons and metals detected in the studied countertop samples have been described as causative of lung inflammation and respiratory disease. Among inorganic constituents, aluminum has been a relevant component within the silicotic nodule, reaching atomic concentrations even higher than silicon in some cases. Such concentrations, both for silicon and aluminum showed a decreasing tendency from the center of the nodule towards its frontier. (© 2021. The Author(s).) |
Databáze: | MEDLINE |
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