Detection of foetal anomaly in advanced maternal age.
| Autor: | Vijayaletchumi T; Hospital Tuanku Ja'afar Seremban, Department of Obstetrics and Gynaecology, Negeri Sembilan, Malaysia., Shuhaila A; Universiti Kebangsaan Malaysia, Faculty of Medicine, Department of Obstetrics and Gynaecology, Kuala Lumpur, Malaysia., Abdul Manaf MR; Universiti Kebangsaan Malaysia, Faculty of Medicine, Department of Community Health, Kuala Lumpur, Malaysia., Nor Azlin MI; Universiti Kebangsaan Malaysia, Faculty of Medicine, Department of Obstetrics and Gynaecology, Kuala Lumpur, Malaysia. azlinm@ppukm.ukm.edu.my. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | The Medical journal of Malaysia [Med J Malaysia] 2021 Nov; Vol. 76 (6), pp. 833-836. |
| Abstrakt: | Objective: The aim of this study was to assess the prevalence of foetal anomaly diagnosed during a detailed ultrasonography amongst patients of advanced maternal age (AMA) and to identify the related anomalies in these age groups. Method: A retrospective observational study amongst AMA mothers was done in Universiti Kebangsaan Malaysia Medical Centre, a Malaysian teaching hospital. The data over a period of three years (January 2013 - December 2016) obtained from the Maternal Foetal Medicine clinic registry was analysed. AMA mothers with singleton pregnancy presenting for foetal structural anomaly scan was included. They were later subdivided into 2 groups (35-39 years and ≥ 40 years). The logistic regression analysis was used to analyse the association of the chromosomal anomalies and the age groups. Results: In all 486 patients were recruited and 84 patients were identified with foetal anomaly (17.3%). There was no significant difference in the prevalence of foetal anomalies or significant association with a specific structural foetal anomaly identified (p>0.05). However, the number of followups for these patients are significantly higher (p<0.001). Conclusion: The prevalence of structural foetal anomalies identified in detailed ultrasonography was low in AMA mothers. Hence, referral criteria for detailed anomaly ultrasonography need to be re-looked. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|