Intraosseous meningioma mimicking osteosarcoma.

Autor:	Delgado R; Mount Sinai Medical Center, The Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Miami Beach, FL, USA., Bahmad HF; Mount Sinai Medical Center, The Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Miami Beach, FL, USA., Bhatia V; Mount Sinai Medical Center, Department of Diagnostic Radiology, Miami Beach, FL, USA., Kantrowitz AB; Mount Sinai Medical Center, Division of Neurosurgery, Miami Beach, FL, USA., Vincentelli C; Mount Sinai Medical Center, The Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Miami Beach, FL, USA.; Florida International University, Herbert Wertheim College of Medicine, Miami, FL, USA.
Jazyk:	angličtina
Zdroj:	Autopsy & case reports [Autops Case Rep] 2021 Oct 29; Vol. 11, pp. e2021332. Date of Electronic Publication: 2021 Oct 29 (Print Publication: 2021).
DOI:	10.4322/acr.2021.332
Abstrakt:	Background: Predominantly intraosseous meningiomas are rare entities that include true primary intraosseous meningiomas (PIM), as well as meningiomas that may show extensive bone involvement, such as en plaque meningiomas. Different hypotheses have been proposed to decipher the origin of PIMs, such as ectopic arachnoid cap cell entrapment during birth or after trauma. Surgical resection is the treatment of choice of such lesions. Case Presentation: We present a case of a 65-year-old man with an enlarging mass in the parieto-occipital region that grew slowly and progressively over 13 years, following head trauma during a motor vehicle accident. One year prior to presentation, he started experiencing daily holocranial headaches and blurry vision. CT and MRI studies revealed a permeative midline calvarial lesion measuring 14 cm in greatest dimension with extensive periosteal reaction, extension into the subcutaneous soft tissues, subjacent dural thickening and intracranial extension with invasion of the superior sagittal sinus. The favored pre-operative clinical diagnosis was osteosarcoma. The abnormal calvarium was excised and histopathological examination confirmed the diagnosis of a predominantly intraosseous calvarial meningioma, WHO grade I. Conclusions: The present case highlights the importance of histopathologic diagnosis in guiding therapeutic decisions and reiterates the necessity of considering PIM or meningiomas with extensive intraosseous component in the differential diagnosis of calvarial masses, even when imaging suggests a neoplasm with aggressive behavior, such as osteosarcoma. Competing Interests: Conflict of interest: None. (Copyright © 2021 The Author(s).)
Databáze:	MEDLINE
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