Transthoracic Vector Flow Imaging in Pediatric Patients with Valvular Stenosis - A Proof of Concept Study.

Autor:	Nguyen TQ; Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark., Bechsgaard T; Department of Radiology, Odense University Hospital, Odense, Denmark., Schmidt MR; Rigshospitalet Hjertecentret, The Heart Center, Copenhagen, Denmark., Juul K; Department of Pediatric Cardiology, Rigshospitalet, Copenhagen, Denmark., Moshavegh R; BK Medical ApS, Herlev, Denmark., Lönn L; Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark., Nielsen MB; Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark., Jensen JA; Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark., Hansen KL; Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.
Jazyk:	angličtina
Zdroj:	Ultrasound international open [Ultrasound Int Open] 2021 Nov 17; Vol. 7 (2), pp. E48-E54. Date of Electronic Publication: 2021 Nov 17 (Print Publication: 2021).
DOI:	10.1055/a-1652-1261
Abstrakt:	Purpose Continuous wave Doppler ultrasound is routinely used to detect cardiac valve stenoses. Vector flow imaging (VFI) is an angle-independent real-time ultrasound method that can quantify flow complexity. We aimed to evaluate if quantification of flow complexity could reliably assess valvular stenosis in pediatric patients. Materials and Methods Nine pediatric patients with echocardiographically confirmed valvular stenosis were included in the study. VFI and Doppler measurements were compared with transvalvular peak-to-peak pressure differences derived from invasive endovascular catheterization. Results Vector concentration correlated with the catheter measurements before intervention after exclusion of one outlier (r=-0.83, p=0.01), whereas the Doppler method did not (r=0.49, p=0.22). The change in vector concentration after intervention correlated strongly with the change in the measured catheter pressure difference (r=-0.86, p=0.003), while Doppler showed a tendency for a moderate correlation (r=0.63, p=0.07). Conclusion Transthoracic flow complexity quantification calculated from VFI data is feasible and may be useful for assessing valvular stenosis severity in pediatric patients. Competing Interests: Conflict of Interest Ramin Moshavegh is employed at BK Medical Aps. Jørgen Arendt Jensen developed and patented the vector flow imaging technique. (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
Databáze:	MEDLINE
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