Iron-Storage Disorder Presenting as Chronic Diarrhea.
| Autor: | Vobugari N; Internal medicine, MedStar Washington Hospital Center, Washington, D.C., USA., Kim J; Gastroenterology and Hepatology, MedStar Georgetown University Hospital, Washington, D.C., USA., Gandhi KD; Internal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA., Lee ZE; Gastroenterology and Hepatology, MedStar Georgetown University Hospital, Washington, D.C., USA., Smith HP; Hematology and Medical Oncology, MedStar Washington Hospital Center, Washington, D.C., USA. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2021 Oct 18; Vol. 13 (10), pp. e18864. Date of Electronic Publication: 2021 Oct 18 (Print Publication: 2021). |
| DOI: | 10.7759/cureus.18864 |
| Abstrakt: | The involvement of the endocrine pancreas leading to bronze diabetes is well studied. However, little is known about the pathophysiology of iron dysregulation involving the exocrine pancreas. We present a unique association between the exocrine pancreas and iron dysregulation. A 45-year-old female presented with chronic diarrhea and low fecal elastase indicative of pancreatic exocrine dysfunction. MRI of the abdomen/pelvis showed iron deposition in the pancreas, suggesting an associated iron-storage disorder without features suggesting chronic pancreatitis. Association of an iron-storage disorder with pancreatic exocrine dysfunction has been reported only in one other case report. Pancreatic exocrine dysfunction can be directly associated with an iron-storage disorder that involves the pancreas. This should be included in the differential and diagnostic work-up of chronic diarrhea of unclear etiology. Based on the literature, we have highlighted the potential pathophysiology relevant to the case. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Vobugari et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|