Host variations in SARS-CoV-2 infection.

Autor: Altiok D; Faculty of Dentistry, Başkent University, Ankara Turkey., Savci EZ; Faculty of Dentistry, Başkent University, Ankara Turkey., Özkara B; Faculty of Dentistry, Başkent University, Ankara Turkey., Alkan K; Faculty of Dentistry, Başkent University, Ankara Turkey., Namdar DS; Faculty of Dentistry, Başkent University, Ankara Turkey., Tunçer G; Faculty of Dentistry, Başkent University, Ankara Turkey.; Faculty of Dentistry, Başkent University, Ankara Turkey., Kilinç BR; Faculty of Dentistry, Başkent University, Ankara Turkey.; Faculty of Dentistry, Başkent University, Ankara Turkey., Suiçmez E; Faculty of Dentistry, Başkent University, Ankara Turkey., Çetin G; Faculty of Dentistry, Başkent University, Ankara Turkey., Ünal S; Faculty of Dentistry, Başkent University, Ankara Turkey., Dönmüş B; Faculty of Dentistry, Başkent University, Ankara Turkey., Karagülleoğlu ZY; Faculty of Dentistry, Başkent University, Ankara Turkey., Uncuoğlu DB; Faculty of Dentistry, Başkent University, Ankara Turkey., Tekeli C; Faculty of Dentistry, Başkent University, Ankara Turkey., Mendi HA; Faculty of Dentistry, Başkent University, Ankara Turkey., Bengi VU; Faculty of Dentistry, Başkent University, Ankara Turkey., Cengiz Seval G; Faculty of Dentistry, Başkent University, Ankara Turkey., Kiliç P; Faculty of Dentistry, Başkent University, Ankara Turkey.; Faculty of Dentistry, Başkent University, Ankara Turkey., Güneş Altuntaş E; Faculty of Dentistry, Başkent University, Ankara Turkey., Demir-Dora D; Faculty of Dentistry, Başkent University, Ankara Turkey.; Faculty of Dentistry, Başkent University, Ankara Turkey.; Faculty of Dentistry, Başkent University, Ankara Turkey.
Jazyk: angličtina
Zdroj: Turkish journal of biology = Turk biyoloji dergisi [Turk J Biol] 2021 Aug 30; Vol. 45 (4), pp. 404-424. Date of Electronic Publication: 2021 Aug 30 (Print Publication: 2021).
DOI: 10.3906/biy-2104-67
Abstrakt: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the zoonotic pathogen that causes the "Coronavirus Disease of 2019 (COVID-19)", and COVID-19 itself is yet to be thoroughly understood. Both the disease as well as the mechanisms by which the host interacts with the SARS-CoV-2 have not been fully enlightened. The epidemiological factors -e.g. age, sex, race-, the polymorphisms of the host proteins, the blood types and individual differences have all been in discussions about affecting the progression and the course of COVID-19 both individually and collectively, as their effects are mostly interwoven. We focused mainly on the effect of polymorphic variants of the host proteins that have been shown to take part in and/or affect the pathogenesis of COVID-19. Additionally, how the procedures of diagnosing and treating COVID-19 are affected by these variants and what possible changes can be implemented are the other questions, which are sought to be answered.
Competing Interests: CONFLICT OF INTEREST: The authors declare there are no competing interests.
(Copyright © 2021 The Author(s).)
Databáze: MEDLINE
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