Molecular docking analysis of phytocompounds from Andrographis paniculata binding with proteins in the notch-signaling pathway.
Autor: | Deiva Suga SS; Department of Microbiology, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India., Krishna Mohan S; Department of Biochemistry and Department of Clinical Skills & Simulation, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India., Sreekandan RN; Department of Clinical Skills & Simulation, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India., K M; Department of Biochemistry and Department of Research, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India., Kamaraj D; Department of Pharmacology, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India., Veeraraghavan VP; Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Velappanchavadi, Chennai-600 077, India., Jayaraman S; Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Velappanchavadi, Chennai-600 077, India., Rajagopal P; Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), West K.K. Nagar, Chennai-600 078, India. |
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Jazyk: | angličtina |
Zdroj: | Bioinformation [Bioinformation] 2020 Nov 30; Vol. 16 (11), pp. 923-928. Date of Electronic Publication: 2020 Nov 30 (Print Publication: 2020). |
DOI: | 10.6026/97320630016923 |
Abstrakt: | It is of interest to document the molecular docking analysis of phytocompounds from Andrographis paniculata binding with protein NOTCH1 in the Notch-signaling pathway in the context of cancer. Hence, we document the binding features of neoandrographolide, 14-deoxyandrographolide, androgapholide and andrograpanin with proteins in the notch-signaling pathway for further consideration. (© 2020 Biomedical Informatics.) |
Databáze: | MEDLINE |
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