Mapping the Conduction System in Patients Undergoing Transcatheter Device Closure of Perimembranous Ventricular Septal Defect: A Proof-of-Concept Study.

Autor: Kaur D; Division of Cardiac Electrophysiology, Department of Cardiology, AIG Hospital, Hyderabad, India., Rajan S; Department of Pediatric Cardiology, MIOT Centre for Children's Cardiac Care, MIOT Hospitals, Chennai, India., Shah M; Department of Cardiology, TATA Main Hospital, Jamshedpur, India., Koneti NR; Department of Pediatric Cardiology, Rainbow Children's Heart Institute, Banjara Hills, Road No. 10, Avenue 4, Hyderabad, Telangana, 500034, India. drkoneti@yahoo.com., Calambur N; Division of Cardiac Electrophysiology, Department of Cardiology, AIG Hospital, Hyderabad, India.
Jazyk: angličtina
Zdroj: Pediatric cardiology [Pediatr Cardiol] 2022 Mar; Vol. 43 (3), pp. 674-684. Date of Electronic Publication: 2021 Nov 21.
DOI: 10.1007/s00246-021-02773-0
Abstrakt: Earlier studies that investigated the relation of atrioventricular (AV) conduction system to perimembranous ventricular septal defect (pmVSD) were based on cardiopathological specimens. To study the relationship of conduction system to pmVSD using 3-dimensional electroanatomic mapping system (EAMS) in patients undergoing device closure. Fifteen consecutive cases of pmVSD from January 2014 to July 2017 (age > 2 years and weight > 8 kg) were included in the study. The course of conduction system and its relationship with the pmVSD was mapped before and after device closure, with the use of EAMS. Median age and weight of the cohort was 10 years (range 4-21 years) and 25 kg (range 13-55) respectively. Device implantation was successful in all patients except 1. The course and relation of the conduction system were posteroinferior to the pmVSD in all cases (100%), and away from the defect in 67% (10/15). In patient with baseline RBBB, the right-sided conduction system was in close proximity to the pmVSD. Two patients had part of left-sided conduction system in close proximity to pmVSD or device edges. Two patients developed RBBB following device deployment, which reverted to normal on follow up. No patient developed high grade AV block during the median follow-up of 34 months (range 24-62). This experimental study has shown the feasibility of 3D EAM of conduction system during device closure of pmVSD. This novel concept can be utilized to understand the anatomy of conduction system in other congenital heart diseases.
(© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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