Influence of drug-related problems on length of hospital stay of women with a history of preeclampsia: A multicenter study.

Autor: Goes AS; Laboratory of Teaching and Research in Social Pharmacy, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, SE, Brazil. Address: Cidade Universitária 'Prof. José Aloísio Campos', Jardim Rosa Elze, São Cristóvão CEP: 49100-000, Brazil., Oliveira AS; Laboratory of Teaching and Research in Social Pharmacy, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, SE, Brazil. Address: Cidade Universitária 'Prof. José Aloísio Campos', Jardim Rosa Elze, São Cristóvão CEP: 49100-000, Brazil., de Andrade TNG; Laboratory of Teaching and Research in Social Pharmacy, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, SE, Brazil. Address: Cidade Universitária 'Prof. José Aloísio Campos', Jardim Rosa Elze, São Cristóvão CEP: 49100-000, Brazil., Alves BMCS; Laboratory of Teaching and Research in Social Pharmacy, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, SE, Brazil. Address: Cidade Universitária 'Prof. José Aloísio Campos', Jardim Rosa Elze, São Cristóvão CEP: 49100-000, Brazil., Neves SJF; Pharmacotherapy Research Group, Institute of Pharmaceutical Sciences, Federal University of Alagos, Maceió, AL, Brazil. Endereço: Campus A. C. Simões. Av. Lourival Melo Mota, se/n, Tabuleiro do Martins, Maceió, Alagoas. CEP: 57072-970., Dias JMG; Departament of Medicine, Federal University of Sergipe, São Cristóvão, SE, Brazil. Address: Cidade Universitária 'Prof. José Aloísio Campos', Jardim Rosa Elze, São Cristóvão CEP: 49100-000, Brasil., de Lyra Júnior DP; Laboratory of Teaching and Research in Social Pharmacy, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, SE, Brazil. Address: Cidade Universitária 'Prof. José Aloísio Campos', Jardim Rosa Elze, São Cristóvão CEP: 49100-000, Brazil., de Oliveira Filho AD; Laboratory of Teaching and Research in Social Pharmacy, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, SE, Brazil. Address: Cidade Universitária 'Prof. José Aloísio Campos', Jardim Rosa Elze, São Cristóvão CEP: 49100-000, Brazil; Pharmacotherapy Research Group, Institute of Pharmaceutical Sciences, Federal University of Alagos, Maceió, AL, Brazil. Endereço: Campus A. C. Simões. Av. Lourival Melo Mota, se/n, Tabuleiro do Martins, Maceió, Alagoas. CEP: 57072-970. Electronic address: alfredo.dias@icf.ufal.br.
Jazyk: angličtina
Zdroj: Pregnancy hypertension [Pregnancy Hypertens] 2022 Mar; Vol. 27, pp. 8-13. Date of Electronic Publication: 2021 Nov 10.
DOI: 10.1016/j.preghy.2021.11.005
Abstrakt: Background: Approximately 5-7 % of pregnant women have hypertension during pregnancy, requiring antihypertensive drug treatment. There have been a lack of studies evaluating how drug-related problems (DRPs) affect morbidity or mortality in the postpartum period among women with a history of preeclampsia.
Objective: To determine the influence of drug-related problems on length of hospital stay of postpartum women with a history of preeclampsia.
Methods: This cross-sectional study included postpartum women diagnosed with preeclampsia, from June to November 2016, in two teaching maternity hospitals in Brazil. The outcomes assessed were, length of hospital stay of postpartum women. The DRPs were classified through the Pharmaceutical Care Network Europe Foundation (PCNE) v 8.01.
Results: 600 women were included, and 354 (59%) were exposed to at least one DRP. The most frequent DRPs were no administration of the prescribed medication, lack of prescription of a medication, although the indication was clear, and ineffectiveness (unknown reason). In patients exposed to DRP, the average length of hospital stay after labour was 5.4 (S.D. 3.6) days versus 4.4 (S.D. 3.3) days in patients non-exposed to DRP (p = 0.0001). The period (in days) to achieve blood pressure control after labour was 4.5 (S.D. 3.5) 3.5 (S.D. 3.2), respectively (p = 0.0001). There were no deaths during the study.
Conclusion and Relevance: Drug-related problems significantly increased the length of hospital stay in postpartum women with a history of preeclampsia.
(Copyright © 2021. Published by Elsevier B.V.)
Databáze: MEDLINE
Externí odkaz: