Oral health-related quality of life in children with osteogenesis imperfecta.

Autor: Cachia Mintoff JM; Eastman Dental Hospital, London, UK.; Great Ormond Street Hospital, London, UK.; Happy Kids Dental Clinic, London, UK., Riddington M; Great Ormond Street Hospital, London, UK.; CAMHS Specialist Eating Disorders Service, Kingsley Green, 15 Forest Lane, Harper Lane, Herts, WD7 9HQ, UK., Parekh S; UCL Eastman Dental Institute, London, UK. s.parekh@ucl.ac.uk.; Department of Paediatric Dentistry, Bloomsbury Campus, Rockefeller Building, 21 University Street, London, WC1E 6DE, UK. s.parekh@ucl.ac.uk.
Jazyk: angličtina
Zdroj: European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry [Eur Arch Paediatr Dent] 2022 Apr; Vol. 23 (2), pp. 261-270. Date of Electronic Publication: 2021 Nov 20.
DOI: 10.1007/s40368-021-00664-9
Abstrakt: Purpose: Osteogenesis imperfecta (OI) results from mutations in the genes involved in the modification or biosynthesis of collagen. This study aimed to assess the oral health-related quality of life (OHRQoL) in children with OI.
Methodology: Participants were recruited from a highly specialised OI centre for children. The Child Oral-Health Impact Profile-Short Form (COHIP-SF) was used, adding demographic and qualitative questions. Children aged 8-16 years participated between January and October 2019. Statistical analysis was carried out. A higher COHIP-SF score indicates better OHRQoL (maximum score, 76).
Results: One hundred and six (106) children participated (44 female, mean age 11.93 years). COHIP-SF median score was 59. Children reporting mild OI (n = 55) had higher median scores (62) compared to severe OI (n = 7) with median scores of 55 (P = 0.087). When comparing mixed (< 12 years, n = 46) and permanent dentition (≥ 12, n = 60), no significant difference in OHRQoL was seen (P = 0.977). There was no significant difference between severities for each COHIP-SF domain. Limited data on the presence of dentinogenesis imperfecta did not impact overall score (P = 0.109), but was significant in the oral-health domain (P = 0.033).
Qualitative: Common themes were the need for braces, discolouration, pain and function.
Conclusion: This study confirmed that children with OI have dental concerns in areas including oral health, functional well-being and socio-emotional well-being. This was related to severity of OI.
(© 2021. Crown.)
Databáze: MEDLINE
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