New Rapid Helicobacter Pylori Blood Test Based on Dual Detection of FliD and CagA Antibodies for On-Site Testing.
| Autor: | Schulz C; Medical Department II, University Hospital, LMU, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site. Electronic address: chr.schulz@med.uni-muenchen.de., Kalali B; Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany., Link A; Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University Magdeburg, Magdeburg, Germany., Gerhard M; Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site., Malfertheiner P; Medical Department II, University Hospital, LMU, Munich, Germany; Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. |
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| Jazyk: | angličtina |
| Zdroj: | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2023 Jan; Vol. 21 (1), pp. 229-231.e1. Date of Electronic Publication: 2021 Nov 16. |
| DOI: | 10.1016/j.cgh.2021.11.008 |
| Abstrakt: | Helicobacter pylori is the most prevalent bacterial infection, affecting half of the world's population, with a high morbidity and mortality rate. 1,2 Several invasive and noninvasive testing procedures are available, and their selective use serves the specific needs of diverse clinical scenarios. For gastric cancer prevention, mass screening is necessary and requires a noninvasive, rapid, accurate and cost-effective test. For this purpose H pylori serology currently seems to be the preferred noninvasive diagnostic method. Population-based testing and treatment for H pylori is cost effective in high-risk countries, but less effective in low- and medium-risk countries. 3,4 Many serologic tests are available on the market, with inconsistent performance often being observed. Therefore, international guidelines recommend considering only serologic tests with high accuracy that have been validated in the respective local populations. To date, no rapid point-of-care test (POCT) has reached a sufficient degree of accuracy. (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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