[Seroprevalence and factors associated with chronic infections among community-dwelling elderly individuals].

Autor: Peixoto SV; Núcleo de Estudos em Saúde Pública e Envelhecimento, Instituto René Rachou, Fiocruz Minas. Av. Augusto de Lima 1715, Barro Preto. 30190-009 Belo Horizonte MG Brasil. sergio.peixoto@fiocruz.br.; Departamento de Gestão em Saúde, Escola de Enfermagem, Universidade Federal de Minas Gerais. Belo Horizonte MG Brasil., Torres KCL; Grupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fiocruz Minas. Belo Horizonte MG Brasil., Teixeira-Carvalho A; Grupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fiocruz Minas. Belo Horizonte MG Brasil., Martins-Filho OA; Grupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fiocruz Minas. Belo Horizonte MG Brasil., Lima-Costa MF
Jazyk: portugalština
Zdroj: Ciencia & saude coletiva [Cien Saude Colet] 2021 Nov 15; Vol. 26 (suppl 3), pp. 5109-5121. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021).
DOI: 10.1590/1413-812320212611.3.37062019
Abstrakt: Chronic infections can contribute to the aging process, but this issue is less studied in Latin America. The aim was to assess the prevalence and factors associated with cytomegalovirus (CMV), Herpes Simplex 1 (HSV-1), Chlamydia pneumoniae and Helicobacter pylori among the elderly. A total of 1,320 individuals participated from the baseline of the Elderly Cohort of Bambuí. IgG antibodies against infections and explanatory variables (sociodemographic factors, health behaviors and health conditions) were evaluated. Poisson regression models with robust variance were used. Seroprevalence rates were 99.4% for CMV, 96.7% for HSV-1, 56% for C. pneumoniae and 70.5% for H. pylori. Elderly men, women, smokers, diabetics, the disabled and those with high levels of IL-6 had a higher prevalence of CMV. HSV-1 was less frequent among women. The prevalence of C. pneumoniae was higher at ages >75 and among diabetics; it was lower among women and individuals with less schooling. H. pylori was less frequent among women and those with detectable levels of IL-1β, but more common among smokers. The findings show a high prevalence of chronic infection and a different epidemiologic profile for each pathogen, making it possible to detect groups that are vulnerable to these infections.
Databáze: MEDLINE