Evaluating the Effect of Low Power Diode Laser 806 nm on the Healing of Unilateral Cleft Lip Scar: An Open-Label Comparative Study.

Autor:	Abdul Mohsen M; 204584Cairo University Hospitals, Cairo, Egypt., El Husseiny Saafan AM; Medical Laser Science of Dental Applications, 531223National Institute of Laser Enhanced Science, Giza, Egypt., El-Basiouny MS; General and Plastic Surgery in 531223National Institute of Laser Enhanced Science, 63526Cairo University, Cairo, Egypt., ElTagy GH; General Surgery Departement, Pediatric Surgery Unit, Cairo University Specialized Pediatric Hospital, Cairo, Egypt., ElBarbary MM; 63526Cairo University, Cairo, Egypt., Ragab M; General Surgery Departement, Pediatric Surgery Unit, Cairo University Specialized Pediatric Hospital, Cairo, Egypt., Emara D; Plastic Surgery Department, Faculty of Medicine, 63526Cairo University, Cairo, Egypt.
Jazyk:	angličtina
Zdroj:	The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association [Cleft Palate Craniofac J] 2023 Jan; Vol. 60 (1), pp. 21-26. Date of Electronic Publication: 2021 Nov 17.
DOI:	10.1177/10556656211053536
Abstrakt:	Objective: To investigate the effect of laser bio-modulation irradiation therapy on the scar after surgical correction of unilateral cleft lip. Design: a comparative, open-label study. Setting: we conducted the study in a university based tertiary hospital that recruited early wound healers of unilateral cleft lip correction. Patients: Eighty patients were divided into two groups: In study's group , patients undergo laser bio-modulation irradiation (n = 60); in the control group , patients were followed-up without intervention (n = 20). Intervention: In the study's group, patients underwent low-power diode Laser with wavelength of 806 nm and power of 100 mw. Main Outcome: The change in the scar of cleft lip patients, which was assessed by clinical examination and ultrasound. Results: The median pigmentation score was significantly lower in the laser group (median = 1; IQR = 1-2) than the control group (median 2; IQR 1-3), with p-value of <0.001. Likewise, the median height score was significantly lower in the laser group (median = 1; IQR = 1-1) than the control group (median 1.5; IQR 1.5-2), with p-value of 0.001. The median pliability score was significantly lower in the laser group (median = 1; IQR = 1-1) than the control group (median 2.5; IQR 1-3), with p-value of <0.001. Finally, the median vascularity score was significantly lower in the laser group (median = 1; IQR = 1-1) than the control group (median 1.5; IQR 1-2), with p-value of <0.001. Conclusion: laser bio-modulation irradiation therapy demonstrates a potential efficacy in managing the hypertrophic scars after surgical repair of unilateral cleft lip.
Databáze:	MEDLINE
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