Regulation of bone metabolism mediated by β-adrenergic receptor and its clinical application.

Autor:	Zhong XP; Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China., Xia WF; Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China. xiawenfang@hust.edu.cn.
Jazyk:	angličtina
Zdroj:	World journal of clinical cases [World J Clin Cases] 2021 Oct 26; Vol. 9 (30), pp. 8967-8973.
DOI:	10.12998/wjcc.v9.i30.8967
Abstrakt:	Recent studies have confirmed that β-adrenergic receptors (β-ARs) are expressed on the surface of osteoblasts and osteoclasts, and that the sympathetic nervous system can regulate bone metabolism by activating them. β-AR blockers (BBs) are commonly used in the treatment of cardiovascular diseases in the elderly. It is important to investigate whether BBs have a beneficial effect on bone metabolism in the treatment of cardiovascular diseases, so as to expand their clinical application. This article reviews the effects of BB on bone metabolism and the progress of clinical research. Competing Interests: Conflict-of-interest statement: The authors declare that they have no conflicting interest. (©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu