[Objective parameters of auditory function in premature infants in the first year of life after taking ototoxic antibiotics].

Autor:	Bogomilsky MR; Pirogov Russian National Research Medical University, Moscow, Russia., Ishanova YS; Pirogov Russian National Research Medical University, Moscow, Russia., Dyakonova IN; Pirogov Russian National Research Medical University, Moscow, Russia., Rakhmanova IV; Pirogov Russian National Research Medical University, Moscow, Russia., Burmistrova DS; Pirogov Russian National Research Medical University, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Vestnik otorinolaringologii [Vestn Otorinolaringol] 2021; Vol. 86 (5), pp. 12-16.
DOI:	10.17116/otorino20218605112
Abstrakt:	Objective: To compare the condition of auditory function during the first year of life according to the registration of distortion product otoacoustic emission (DPOAE) and short-latency evoked potentials (SLEP) in premature infants who received ototoxic antibiotics to those ones, who did not. Material and Methods: Auditory function was examined in 145 premature infants. Auditory assessment was carried out by registration of DPOAEs, SLEPs and tympanometry. Statistical processing was performed using the program Statgraphics Centurion XV. Results: In this study, according to DPOAE, the average response values of the cochlea in premature infants who had a history of ototoxic therapy, undergo final changes after children reach the age of 6 months. The study of latent periods and threshold values of the V peak of SLEP showed a delay in the maturation process of the perceiving and conducting auditory structures during the first year of life in children who received ototoxic antibiotics in the first month of life. Conclusion: We evaluated the timing of the completion of response changes in children of the control group using the DPOAE and SLEP registration data. In children of the study group, we evaluated the effect of the administered ototoxic antibiotics. Timing of audiological control of the hearing organ condition are demonstrated for premature children after ototoxicosis, required methods of its examination are established.
Databáze:	MEDLINE
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