Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication.

Autor: Yurtman E; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Özer O; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.; Emmy Noether Group Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön, Germany., Yüncü E; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Dağtaş ND; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Koptekin D; Department of Health Informatics, Middle East Technical University, Ankara, Turkey., Çakan YG; Department of Prehistory, Istanbul University, Laleli, Istanbul, Turkey., Özkan M; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Akbaba A; Department of Anthropology, Ankara University, Ankara, Turkey., Kaptan D; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Atağ G; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Vural KB; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Gündem CY; Department of Archaeology, Batman University, Batman, Turkey., Martin L; Institute of Archaeology, University College London, London, UK., Kılınç GM; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.; Department of Bioinformatics, Graduate School of Health Sciences, Hacettepe University, Ankara, Turkey., Ghalichi A; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.; Department of Archaeogenetics, Max-Planck Institute for the Science of Human History, Jena, Germany., Açan SC; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Yaka R; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Sağlıcan E; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Lagerholm VK; Archaeological Research Laboratory, Department of Archaeology and Classical Studies, University of Stockholm, Stockholm, Sweden., Krzewińska M; Archaeological Research Laboratory, Department of Archaeology and Classical Studies, University of Stockholm, Stockholm, Sweden., Günther T; Department of Organismal Biology, Human Evolution Research Program, Uppsala University, Uppsala, Sweden., Morell Miranda P; Department of Organismal Biology, Human Evolution Research Program, Uppsala University, Uppsala, Sweden., Pişkin E; Department of Settlement Archaeology, Middle East Technical University, Ankara, Turkey., Şevketoğlu M; Centre for Archaeology, Cultural Heritage and Conservation, Cyprus International University, Nicosia, Cyprus., Bilgin CC; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Atakuman Ç; Department of Settlement Archaeology, Middle East Technical University, Ankara, Turkey., Erdal YS; Department of Anthropology, Hacettepe University, Ankara, Turkey.; Molecular Anthropology Group (Human_G), Hacettepe University, Ankara, Turkey., Sürer E; Department of Modeling and Simulation, Graduate School of Informatics, Middle East Technical University, Ankara, Turkey., Altınışık NE; Department of Anthropology, Hacettepe University, Ankara, Turkey.; Molecular Anthropology Group (Human_G), Hacettepe University, Ankara, Turkey., Lenstra JA; Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., Yorulmaz S; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Abazari MF; Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran., Hoseinzadeh J; Department of Archaeology, University of Kashan, Kashan, Iran., Baird D; Department of Archaeology, Classics, and Egyptology, University of Liverpool, Liverpool, UK., Bıçakçı E; Department of Prehistory, Istanbul University, Laleli, Istanbul, Turkey., Çevik Ö; Department of Archaeology, Trakya University, Edirne, Turkey., Gerritsen F; Netherlands Institute in Turkey, Istanbul, Turkey., Özbal R; Department of Archaeology and History of Art, Koç University, Istanbul, Turkey., Götherström A; Archaeological Research Laboratory, Department of Archaeology and Classical Studies, University of Stockholm, Stockholm, Sweden., Somel M; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey. msomel@metu.edu.tr., Togan İ; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey., Özer F; Department of Anthropology, Hacettepe University, Ankara, Turkey. fusunozer@hacettepe.edu.tr.; Molecular Anthropology Group (Human_G), Hacettepe University, Ankara, Turkey. fusunozer@hacettepe.edu.tr.
Jazyk: angličtina
Zdroj: Communications biology [Commun Biol] 2021 Nov 12; Vol. 4 (1), pp. 1279. Date of Electronic Publication: 2021 Nov 12.
DOI: 10.1038/s42003-021-02794-8
Abstrakt: Sheep were among the first domesticated animals, but their demographic history is little understood. Here we analyzed nuclear polymorphism and mitochondrial data (mtDNA) from ancient central and west Anatolian sheep dating from Epipaleolithic to late Neolithic, comparatively with modern-day breeds and central Asian Neolithic/Bronze Age sheep (OBI). Analyzing ancient nuclear data, we found that Anatolian Neolithic sheep (ANS) are genetically closest to present-day European breeds relative to Asian breeds, a conclusion supported by mtDNA haplogroup frequencies. In contrast, OBI showed higher genetic affinity to present-day Asian breeds. These results suggest that the east-west genetic structure observed in present-day breeds had already emerged by 6000 BCE, hinting at multiple sheep domestication episodes or early wild introgression in southwest Asia. Furthermore, we found that ANS are genetically distinct from all modern breeds. Our results suggest that European and Anatolian domestic sheep gene pools have been strongly remolded since the Neolithic.
(© 2021. The Author(s).)
Databáze: MEDLINE
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