| Autor: |
Mazerkina NA; Burdenko Neurosurgery Institute., Savateev AN; Business Center for Neurosurgery., Gorelyshev SK; Burdenko Neurosurgery Institute., Mariashev SA; Burdenko Neurosurgery Institute., Beregovskaya SA; Сenter for therapy and preventive medicine., Konovalov AN; Burdenko Neurosurgery Institute. |
| Jazyk: |
ruština |
| Zdroj: |
Problemy endokrinologii [Probl Endokrinol (Mosk)] 2021 Oct 03; Vol. 67 (5), pp. 58-66. Date of Electronic Publication: 2021 Oct 03. |
| DOI: |
10.14341/probl12723 |
| Abstrakt: |
We describe a 15-year girl, who developed panhypopituitarism and diencephalic obesity after surgical excision of craniopharyngioma, followed by nonalcoholic fatty liver disease and cirrhosis 5 years after surgery. Cirrhosis in this case manifested by hypoxia due to hepatopulmonary syndrome, and despite cure of craniopharyngioma by surgery and radiosurgery treatment and adequate hormonal substitution therapy patient died 9 years after surgery. Growth hormone substitutional therapy in patients with hypopituitarism, and steatohepatitis may decrease liver triglyceride accumulation and prevent end-stage liver disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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