Imaging of chemotherapy-induced liver toxicity: an illustrated overview.
Autor: | Torri GB; Department of Radiology, Hospital de Aeronáutica de Canoas, Canoas, RS 92200630, Brazil., Soldatelli MD; Department of Radiology, Beneficência Portuguesa de São Paulo, São Paulo, SP 01323001, Brazil., Luersen GF; Department of Radiology, Hospital da Cruz Vermelha Portuguesa, Lisboa, 1549008, Portugal.; Department of Radiology, Hospital CUF Tejo, Lisboa, 1350352, Portugal.; Affidea group, Lisboa, Portugal., Almeida Ghezzi CL; Department of Radiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS 90035903, Brazil.; Department of Radiology, Hospital Moinhos de Vento, Porto Alegre, RS 90035000, Brazil. |
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Jazyk: | angličtina |
Zdroj: | Hepatic oncology [Hepat Oncol] 2021 Sep 15; Vol. 8 (4), pp. HEP32. Date of Electronic Publication: 2021 Sep 15 (Print Publication: 2021). |
DOI: | 10.2217/hep-2020-0026 |
Abstrakt: | Chemotherapy is a potential cause of focal and diffuse hepatobiliary lesions. Many of these lesions may be demonstrated on imaging, especially computed tomography and MRI. Some of these lesions, especially those of steatosis and sinusoidal obstruction syndrome, are associated with a worse prognosis and risk of hepatic failure in the context of surgical management. Notably, some chemotherapy-induced hepatic alterations, such as sinusoidal obstruction syndrome, pseudocirrhosis and focal hepatopathies, may be mistakenly interpreted as signs of cancer progression, misguiding the therapeutic planning for patients receiving chemotherapy. Competing Interests: Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript. (© 2021 Giovanni Brondani Torri and authors.) |
Databáze: | MEDLINE |
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