Nd:YAG capsulotomy incidence associated with five different single-piece monofocal intraocular lenses: a 3-year Spanish real-world evidence study of 8293 eyes.

Autor: Belda JI; Hospital Universitario de Torrevieja, Torrevieja, Alicante, Spain., Dabán JP; Hospital Universitario de Torrevieja, Torrevieja, Alicante, Spain., Elvira JC; Hospital Universitario del Vinalopó, Elche, Alicante, Spain., O'Boyle D; Alcon Laboratories Ireland Ltd., Cork, Ireland. derek.oboyle@Alcon.com., Puig X; Alcon Healthcare, SA, Barcelona, Spain., Pérez-Vives C; Alcon Management SA, Cointrin, Switzerland., Zou M; IQVIA Real World Solutions, Basel, Switzerland., Sun S; IQVIA Real World Solutions, Basel, Switzerland.
Jazyk: angličtina
Zdroj: Eye (London, England) [Eye (Lond)] 2022 Nov; Vol. 36 (11), pp. 2205-2210. Date of Electronic Publication: 2021 Nov 11.
DOI: 10.1038/s41433-021-01828-z
Abstrakt: Objectives: To investigate the associations between different single-piece monofocal intraocular lenses (IOLs) and neodymium-doped yttrium aluminum garnet laser (Nd:YAG) capsulotomy incidence 3 years after cataract surgery in a Spanish cohort.
Methods: This is a longitudinal retrospective cohort study. Data were extracted from the electronic medical records of two large regional hospitals in Spain. Patients aged ≥65 years receiving cataract surgery with placement of five different IOLs and with ≥6 months of baseline data were included. We report the Nd:YAG capsulotomy incidence 3 years post cataract surgery, and the survival plot over the 3 years of follow-up time. The associated adjusted (age, gender, and diabetic retinopathy) multivariate analysis with odds ratios (ORs) and 95% CIs is also presented.
Results: The cohort (53% female, mean age 75 ± 5.9 years) included 14,519 eyes (Alcon AcrySof = 2968, AJL LLASY60 = 1776, Medicontur Bi-flex = 5176, Zeiss Asphina = 4478, and IOL Tech Stabibag = 121). Of these, 8293 were retained until 3-year follow-up. At 3 years after cataract surgery, the Nd:YAG capsulotomy incidence was 5% for Alcon AcrySof, while it ranged from 21.2% to 31.1% for the other IOLs (p < 0.0001 for each comparison). The odds for Nd:YAG capsulotomy were significantly higher (p < 0.0001) for other IOLs compared with those of Alcon AcrySof (ORs = 8.85, 5.86, 5.74, 5.21 for AJL LLASY60, Medicontur Bi-flex, IOL Tech Stabibag, and Zeiss Asphina, respectively).
Conclusions: The lower Nd:YAG capsulotomy rates for Alcon AcrySof IOLs compared to the other IOLs support the importance of lens choice in reducing patient burden and treatment costs.
(© 2021. The Author(s).)
Databáze: MEDLINE
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