Voltage-induced fluorescence lifetime imaging of a BODIPY derivative in giant unilamellar vesicles as potential neuron membrane mimics.

Autor: Sirbu D; School of Mathematics, Statistics & Physics, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK. dumitru.sirbu@ncl.ac.uk., Zeng L; Molecular Photonics Laboratory, Chemistry-School of Natural & Environmental Sciences, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK. andrew.benniston@ncl.ac.uk., Waddell PG; Crystallography Laboratory, Chemistry-School of Natural & Environmental Sciences, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK., Tkachenko NV; Faculty of Engineering and Natural Sciences, Tampere University, Tampere, Finland., Botchway SW; Central Laser Facility, Rutherford Appleton Laboratory, Harwell, Oxford, OX11 0QX, UK., Benniston AC; Molecular Photonics Laboratory, Chemistry-School of Natural & Environmental Sciences, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK. andrew.benniston@ncl.ac.uk.
Jazyk: angličtina
Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Nov 25; Vol. 57 (94), pp. 12631-12634. Date of Electronic Publication: 2021 Nov 25.
DOI: 10.1039/d1cc03756k
Abstrakt: Fluorescence lifetime imaging (FLIM) was used to study the behaviour of a BODIPY dye in a giant unilamellar vesicle (GUV) in the presence of an electric field. The modulation of the electric field resulted in distinctive fluorescence lifetime changes in line with environment alterations within the membrane mimic.
Databáze: MEDLINE