N95 respirator and surgical mask effectiveness against respiratory viral illnesses in the healthcare setting: A systematic review and meta-analysis.

Autor: Collins AP; University of Central Florida College of Medicine Orlando Florida USA., Service BC; Orlando Health Orthopedic Institute Orlando Florida USA., Gupta S; Department of Orthopedics University of Pennsylvania Philadelphia Pennsylvania USA., Mubarak N; University of Central Florida College of Medicine Orlando Florida USA., Zeini IM; AdventHealth Orthopedic Institute Orlando Florida USA., Osbahr DC; Orthopaedic Surgery, Rothman Orthopaedic Institute Florida Orlando Florida USA., Romeo AA; DuPage Medical Group Musculoskeletal Institute Chicago Illinois USA.
Jazyk: angličtina
Zdroj: Journal of the American College of Emergency Physicians open [J Am Coll Emerg Physicians Open] 2021 Oct 28; Vol. 2 (5), pp. e12582. Date of Electronic Publication: 2021 Oct 28 (Print Publication: 2021).
DOI: 10.1002/emp2.12582
Abstrakt: Objective: To examine the results, level of evidence, and methodologic quality of original studies regarding surgical mask effectiveness in minimizing viral respiratory illness transmission, and, in particular, the performance of the N95 respirator versus surgical mask.
Methods: Meta-analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines with use of PubMed, MEDLINE, and the Cochrane Library databases.
Results: Eight studies (9164 participants) were included after screening 153 articles. Analyses showed statistically significant differences between N95 respirator versus surgical mask use to prevent influenza-like-illness (risk ratio [RR] = 0.81, 95% confidence interval [CI] = 0.68-0.94, P  < 0.05), non-influenza respiratory viral infection (RR = 0.62, 95% CI = 0.52-0.74, P  < 0.05), respiratory viral infection (RR = 0.73, 95% CI = 0.65-0.82, P  < 0.05), severe acute respiratory syndrome coronavirus (SARS-CoV) 1 and 2 virus infection (RR = 0.17, 95% CI = 0.06-0.49, P  < 0.05), and laboratory-confirmed respiratory viral infection (RR = 0.75, 95% CI = 0.66-0.84, P  < 0.05). Analyses did not indicate statistically significant results against laboratory-confirmed influenza (RR = 0.87, CI = 0.74-1.03, P  > 0.05).
Conclusions: N95 respirator use was associated with fewer viral infectious episodes for healthcare workers compared with surgical masks. The N95 respirator was most effective in reducing the risk of a viral infection in the hospital setting from the SARS-CoV 1 and 2 viruses compared to the other viruses included in this investigation. Methodologic quality, risk of biases, and small number of original studies indicate the necessity for further research to be performed, especially in front-line healthcare delivery settings.
Competing Interests: The authors report no conflicts of interest pertaining to this work. For full listing of conflicts of interest, please see American Academy of Orthopaedic Surgeons Conflicts of Interest disclosures.
(© 2021 The Authors. JACEP Open published by Wiley Periodicals LLC on behalf of American College of Emergency Physicians.)
Databáze: MEDLINE
Externí odkaz: