Fast and selective synthesis of mono-substituted sucrose methacrylate ester monomer.

Autor: Rojas Sterling JC; Universidad Santiago de Cali (USC), Facultad de Ciencias Básicas - Campus Pampalinda, Santiago de Cali, Colombia., Ortega JO; Universidad Santiago de Cali (USC), Facultad de Ciencias Básicas - Campus Pampalinda, Santiago de Cali, Colombia; Sao Paulo State University (UNESP-IBILCE), Department of Chemistry and Environmental Sciences, Sao Jose Do Rio Preto, SP, Brazil., Metzker G; Sao Paulo State University (UNESP-IBILCE), Department of Chemistry and Environmental Sciences, Sao Jose Do Rio Preto, SP, Brazil., Boscolo M; Sao Paulo State University (UNESP-IBILCE), Department of Chemistry and Environmental Sciences, Sao Jose Do Rio Preto, SP, Brazil., Mora Vargas JA; Sao Paulo State University (UNESP-IBILCE), Department of Chemistry and Environmental Sciences, Sao Jose Do Rio Preto, SP, Brazil. Electronic address: jamvargas@usp.br.
Jazyk: angličtina
Zdroj: Carbohydrate research [Carbohydr Res] 2022 Jan; Vol. 511, pp. 108465. Date of Electronic Publication: 2021 Oct 30.
DOI: 10.1016/j.carres.2021.108465
Abstrakt: Sucrose methacrylate (SM) is a key monomer for synthesizing biocompatible polymers with a carbohydrate core. However, controlled SM synthesis is challenging due to the possible formation of regio-isomers. This study describes SM synthesis that involves ultrasound irradiation of a homogeneous basic medium. The selectivity for mono-substituted SM was 86% within 30 min of reaction. The newly developed methodology is faster and more selective than that of mono-substituted SM synthesis already described in the literature.
(Copyright © 2021 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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