Does interatrial communication affect post-operative course of children undergoing tetralogy of Fallot repair? Single centre retrospective cohort study: propensity score matching.

Autor: Kabbani MS; Cardiac Science Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia., Jijeh A; Cardiac Science Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Diraneyya OM; Cardiac Science Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Basakran FA; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Bin Sabbar NS; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Fatima A; Cardiac Science Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia., AlEraij SM; Department of Family Medicine, King Saud University Medical City, Riyadh, Saudi Arabia., Alshahrani WA; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Ardah HI; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; Department of Biostatistics and Bioinformatics, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia., Shaath GA; Cardiac Science Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Cardiology in the young [Cardiol Young] 2021 Nov 05, pp. 1-6. Date of Electronic Publication: 2021 Nov 05.
DOI: 10.1017/S1047951121004431
Abstrakt: Introduction: During tetralogy of Fallot repair, leaving or even create an interatrial communication may facilitate post-operative course particularly with right ventricle restrictive physiology. The aim of our study is to assess the influence of atrial communication on post-operative course of tetralogy of Fallot repair.
Methods: Retrospectively, we studied all children who had tetralogy of Fallot repair (2003-2018). We divided them into two groups: tetralogy of Fallot repair with interatrial communication (TOFASD) group and tetralogy of Fallot repair with intact atrial septum (TOFIAS) group. We performed propensity match score for specific pre- or intra-operative variables and compared groups for post-operative outcome variables. Secondarily, we looked for right ventricle restrictive physiology incidence and influence of early repair performed before 3 months of age on post-operative course.
Results: One hundred and sixty children underwent tetralogy of Fallot repair including (93) cases of TOFIAS (58%) and (67) cases of TOFASD (42%). With propensity matching score, 52 patients from each group were compared. Post-operative course was indifferent in term of positive pressure ventilation time, vasoactive inotropic score, creatinine and lactic acid levels, duration and amount of chest drainage and length of intensive care unit and hospital stay. Right ventricle restrictive physiology occurred in 38% of patients with no effects on outcome. 12/104 patients (12%) with early repair needed longer pressure ventilation time (p = 0.003) and intensive care unit stay (p = 0.02).
Conclusion: Leaving interatrial communication in tetralogy of Fallot repair did not affect post-operative course. As well, right ventricle restrictive physiology did not affect post-operative course. Infants undergoing early tetralogy of Fallot repair may require longer duration of positive pressure ventilation time and intensive care unit stay.
Databáze: MEDLINE