Massively parallel sequencing in hereditary prostate cancer families reveals a rare risk variant in the DNA repair gene, RAD51C.

Autor: Marthick JR; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia., Raspin K; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia., Foley GR; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia., Blackburn NB; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia., Banks A; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia., Donovan S; Hobart Pathology, Hobart, TAS, 7000, Australia., Malley RC; Hobart Pathology, Hobart, TAS, 7000, Australia; School of Medicine, University of Tasmania, Hobart, TAS, 7000, Australia., Field MA; Centre for Tropical Bioinformatics and Molecular Biology and Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, 4878, Australia; Genome Informatics, John Curtin School of Medical Research, Australian National University, Canberra., Stanford JL; Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., M4-B874, Seattle, WA 98109-1024, USA., Ostrander EA; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., FitzGerald LM; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia., Dickinson JL; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia. Electronic address: jo.dickinson@utas.edu.au.
Jazyk: angličtina
Zdroj: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2021 Dec; Vol. 159, pp. 52-55. Date of Electronic Publication: 2021 Nov 01.
DOI: 10.1016/j.ejca.2021.09.038
Abstrakt: Competing Interests: Conflict of interest statement The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Databáze: MEDLINE