Echocardiographic findings in patent ductus arteriosus-associated infective endarteritis.
| Autor: | Saucedo-Orozco H; Department of Cardioneumology, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social; Mexico City-México., Vargas-Barrón J; Department of Pharmacology, Instituto Nacional de Cardiología Ignacio Chávez; Mexico City-México., Vázquez-Antona CA; Department of Pediatric Echocardiography, Instituto Nacional de Cardiología Ignacio Chávez; Mexico City-México., Castillo-Castellón F; Department of Tomography, Instituto Nacional de Cardiología Ignacio Chávez; Mexico City-México. |
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| Jazyk: | angličtina |
| Zdroj: | Anatolian journal of cardiology [Anatol J Cardiol] 2021 Nov; Vol. 25 (11), pp. 774-780. |
| DOI: | 10.5152/AnatolJCardiol.2021.36156 |
| Abstrakt: | Background: Infectious endarteritis associated with patent ductus arteriosus (PDA-IE) is an uncommon complication in the era of antibiotics. However, it implies a clinical challenge in patients with a fever of undetermined origin; Two-dimensional transthoracic echocardiography (TTE) performs a fundamental role in diagnosis and follow-up. Methods: A retrospective analysis was then made of the data of all patients admitted at our center with PDA-IE within 15 years, and a review of the literature regarding diagnosis, TTE findings, and treatment was performed. Results: A total of 17 patients were identified. The mean age was 17.8 years. The TTE done in all patients confirmed the PDA and PA vegetations diagnosis; in five cases, one vegetation was present; in three cases, two vegetations were found, and in the nine remaining cases, three or more vegetations were observed. In two-thirds of the cases, the vegetations' size was 3 to 28 mm, and the principal morphology was filiform. In all cases, at least one of the vegetations was developed in the DA's lateral wall. Pulmonary valve (PV) was affected in 41% of the patients and caused low to moderate valvular regurgitation. Pulmonary embolism was present in 7 cases and pulmonary aneurism in one case. Conclusions: Decreased incidence of PDA-IE has been currently achieved with early antibiotic therapy. However, today, this complication carries a significant risk of valve damage and other cardiac structures' involvement. |
| Databáze: | MEDLINE |
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