A lifestyle pattern during adolescence is associated with cardiovascular risk markers in young adults: results from the DONALD cohort study.

Autor:	Schnermann ME; Institute of Nutrition and Food Sciences, Nutritional Epidemiology, University of Bonn, Bonn, Germany., Schulz CA; Institute of Nutrition and Food Sciences, Nutritional Epidemiology, University of Bonn, Bonn, Germany., Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research, Düsseldorf, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Alexy U; Institute of Nutrition and Food Sciences, Nutritional Epidemiology, University of Bonn, Bonn, Germany., Nöthlings U; Institute of Nutrition and Food Sciences, Nutritional Epidemiology, University of Bonn, Bonn, Germany.
Jazyk:	angličtina
Zdroj:	Journal of nutritional science [J Nutr Sci] 2021 Oct 12; Vol. 10, pp. e92. Date of Electronic Publication: 2021 Oct 12 (Print Publication: 2021).
DOI:	10.1017/jns.2021.84
Abstrakt:	Lifestyle score approaches combining individual lifestyle factors, e.g. favourable diet, physical activity or normal body weight, showed inverse associations with cardiovascular disease (CVD) risk. However, research mainly focussed on adult behaviour and is scarce for vulnerable time windows for adult health like adolescence. We investigated associations between an adolescent lifestyle score and CVD risk markers in young adulthood. Overall, we analysed 270 participants of the open DONALD cohort study with 1-6 complete measurements of five lifestyle factors (healthy diet, moderate-to-vigorous physical activity, sedentary behaviour, sleep duration and BMI standard deviation score) during adolescence (females: 8⋅5-15⋅5 years and males: 9⋅5-16⋅5 years). Multivariable linear regression models were used to investigate the prospective association between the adolescent lifestyle score (0-5 points) and CVD risk markers in young adulthood (18-30 years). On average, participants obtained a mean adolescent lifestyle score of 2⋅9 (0-5) points. Inverse associations between the adolescent lifestyle score and waist circumference, waist-to-height ratio and percentage of body fat were observed (4⋅1, 4⋅1 and 9⋅2 % decrease per 1 point increase in adolescent lifestyle score, respectively, P < 0⋅05). For the remaining CVD risk markers (glucose, blood lipids, blood pressure and a proinflammatory score), no associations were observed. A healthy adolescent lifestyle is particularly associated with CVD risk-related favourable anthropometric markers in adulthood. A more comprehensive understanding of lifestyle patterns in the life course might enable earlier, targeted preventive measures to assist vulnerable groups in prevention of chronic diseases. (© The Author(s) 2021.)
Databáze:	MEDLINE
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