Fibrin-Associated Diffuse Large B Cell Lymphoma Found on Revision Arthroplasty of the Knee.

Autor: Hall J; From the Departments of Pathology, Orthopedic Surgery, Radiation Oncology, and Hematology Oncology, Brooke Army Medical Center, Joint Base San Antonio, Texas., Kampfer C; From the Departments of Pathology, Orthopedic Surgery, Radiation Oncology, and Hematology Oncology, Brooke Army Medical Center, Joint Base San Antonio, Texas., Williams N; From the Departments of Pathology, Orthopedic Surgery, Radiation Oncology, and Hematology Oncology, Brooke Army Medical Center, Joint Base San Antonio, Texas., Osswald M; From the Departments of Pathology, Orthopedic Surgery, Radiation Oncology, and Hematology Oncology, Brooke Army Medical Center, Joint Base San Antonio, Texas., Bishop B; From the Departments of Pathology, Orthopedic Surgery, Radiation Oncology, and Hematology Oncology, Brooke Army Medical Center, Joint Base San Antonio, Texas., Hall M; From the Departments of Pathology, Orthopedic Surgery, Radiation Oncology, and Hematology Oncology, Brooke Army Medical Center, Joint Base San Antonio, Texas., Alderete J; From the Departments of Pathology, Orthopedic Surgery, Radiation Oncology, and Hematology Oncology, Brooke Army Medical Center, Joint Base San Antonio, Texas.
Jazyk: angličtina
Zdroj: Southern medical journal [South Med J] 2021 Nov; Vol. 114 (11), pp. 708-713.
DOI: 10.14423/SMJ.0000000000001321
Abstrakt: Fibrin-associated diffuse large B cell lymphoma (FA-DLBCL) is a rare Epstein-Barr viruspositive B cell lymphoma that is nonmass-forming, does not directly produce symptoms, and is incidentally discovered on histological examination of tissues excised for other reasons. Despite overlap in morphologic and immunophenotypic features with aggressive B cell neoplasms, FA-DLBCL shows an excellent clinical outcome, even with surgical excision alone. We report an extremely rare occurrence of FA-DLBCL found in association with a metallic implant on revision arthroplasty of the knee. This report also illustrates the need for an integrated multidisciplinary approach for accurate diagnosis and avoidance of overtreatment.
Databáze: MEDLINE
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