Stability of SARS-CoV-2 and other airborne viruses under different stress conditions.

Autor: Fumagalli MJ; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes 3900, Vila Monte Alegre, Ribeirão Preto, 140490-900, Brazil. marcilio_jorge@hotmail.com., Capato CF; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes 3900, Vila Monte Alegre, Ribeirão Preto, 140490-900, Brazil., de Castro-Jorge LA; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes 3900, Vila Monte Alegre, Ribeirão Preto, 140490-900, Brazil., de Souza WM; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes 3900, Vila Monte Alegre, Ribeirão Preto, 140490-900, Brazil., Arruda E; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes 3900, Vila Monte Alegre, Ribeirão Preto, 140490-900, Brazil., Figueiredo LTM; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes 3900, Vila Monte Alegre, Ribeirão Preto, 140490-900, Brazil.
Jazyk: angličtina
Zdroj: Archives of virology [Arch Virol] 2022 Jan; Vol. 167 (1), pp. 183-187. Date of Electronic Publication: 2021 Nov 02.
DOI: 10.1007/s00705-021-05293-7
Abstrakt: Viral stability under stress conditions may directly affect viral dissemination, seasonality, and pathogenesis. We exposed airborne viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mumps virus, coxsackievirus B5, human rhinovirus A16, and respiratory syncytial virus, to different temperatures, UV light exposure time, pH values, and osmotic pressures and measured the remaining viral infectivity. Reduced thermal stability was observed for coxsackievirus B5 at 45 °C, while SARS-CoV-2 demonstrated residual infectivity at 55 °C. UV light exposure was an efficient means of viral inactivation but was less efficient for non-enveloped viruses. Rhinovirus A16 and respiratory syncytial virus demonstrated extreme sensitivity to acid conditions, while SARS-CoV-2, rhinovirus A16, and respiratory syncytial virus were unstable in an alkaline environment. The information obtained in this study will be useful for the development of viral inactivation methods and may be correlated with epidemiological and seasonal viral characteristics.
(© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: