Parameters of cutaneous microvasculature in men of working age with newly diagnosed arterial hypertension.

Autor: Korolev AI; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Fedorovich AA; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia.; FSBI SRC RF 'Institute of Biomedical Problems' RAS, Moscow, Russia., Gorshkov AY; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Dadaeva VA; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Kim OT; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Omelyanenko KV; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Mikhaylova MA; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Vasilyev DK; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Dzhioeva ON; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Akasheva DU; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia., Drapkina OM; FSBI 'National Health and Research Center of Preventive Healthcare' of the Ministry of Health of Russia, Moscow, Russia.
Jazyk: angličtina
Zdroj: Clinical hemorheology and microcirculation [Clin Hemorheol Microcirc] 2022; Vol. 80 (4), pp. 373-387.
DOI: 10.3233/CH-211292
Abstrakt: Objective: To investigate structural and functional features of cutaneous microvasculature in men of working age with newly diagnosed arterial hypertension (AH).
Materials and Methods: The study included 161 apparently healthy men from 30 to 60 years, who underwent a comprehensive examination of cardiovascular system "from the heart to the capillaries". Control group (CG) included 60 normotensive men. AH group included 101 men with elevated BP.
Results: There is no rarefaction of the capillary bed and latent fluid retention in the interstitial space in the skin in men with AH. No data were obtained for increased endothelial, neurogenic and myogenic tone of resistive cutaneous precapillary arterioles in AH group, but a decrease in the perfusion efficiency of the endothelial and myogenic mechanisms of tissue perfusion modulation was noted.
Conclusion: Obtained results allow making the assumption that metabolic disorders at the level of capillaries that are of a systemic nature prevail in men with the onset of AH.
Databáze: MEDLINE
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