Assessment of mortality from COVID-19 in a multicultural multi-ethnic patient population.

Autor: Nair SC; Department of Academic Affairs, College of Medicine & Health Sciences, Tawam Hospital, UAE University, Academic Affairs, Post Box 15258, Al Ain, UAE. schandra@seha.ae., Gasmelseed HI; Department of Infectious Diseases, Internal Medicine, Al Ain Hospital, Al Ain, UAE., Khan AA; Department of Infectious Diseases, Internal Medicine, Tawam Hospital, Al Ain, UAE., Khafagy IN; Department of Pharmacy, Al Ain Hospital, Al Ain, UAE., Sreedharan J; Department of Community Medicine, Gulf Medical University, Ajman, UAE., Saleem AA; Department of Infectious Diseases, Internal Medicine, Tawam Hospital, Al Ain, UAE., Abdrhman HI; Department of Infectious Diseases, Internal Medicine, Al Ain Hospital, Al Ain, UAE., Alhosani AH; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Siddiqua AR; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Ahmed AR; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Shubbar AI; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Aleissaee AR; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Alanqar AW; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Hamadeh AM; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Safdani FA; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Habbal FW; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Choker HB; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Bashir KM; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Alblooshi MA; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Farajallah MM; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Alzaabi MN; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Shil RS; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Alshehhi SS; Department of Academic Affairs, Internal Medicine, Tawam Hospital, Al Ain, UAE., Douleh WF; Department of Infectious Disease, Internal Medicine, Al Ain Hospital, Al Ain, UAE.
Jazyk: angličtina
Zdroj: BMC infectious diseases [BMC Infect Dis] 2021 Oct 29; Vol. 21 (1), pp. 1115. Date of Electronic Publication: 2021 Oct 29.
DOI: 10.1186/s12879-021-06762-9
Abstrakt: Background: Studies indicate that ethnicity and socioeconomic disparity are significant facilitators for COVID-19 mortality. The United Arab Emirates, distinctly has a population of almost 12% citizens and the rest, immigrants, are mainly unskilled labourers. The disparate socio-economic structure, crowded housing conditions, and multi-ethnic population offer a unique set of challenges in COVID-19 management.
Methods: Patient characteristics, comorbidities, and clinical outcomes data from the electronic patient medical records were retrospectively extracted from the hospital information system of the two designated public COVID-19 referral hospitals. Chi-square test, logistic regression, and odds ratio were used to analyse the variables.
Results: From, the total of 3072 patients, less than one-fifth were females; the Asian population (71.2%);followed by Middle Eastern Arabs (23.3%) were the most infected by the virus. Diabetes Mellitus (26.8%), hypertension (25.7%) and heart disease (9.6%) were the most prevalent comorbidities observed among COVID-19 patients. Kidney disease as comorbidity significantly diminished the survival rates (Crude OR 9.6, 95% CI (5.6-16.6), p < 0.001) and (Adjusted OR 5.7 95% CI (3.0 - 10.8), p < 0.001), as compared to those patients without kidney disease. Similarly, the higher age of patients between 51 and 65 years, significantly decreased the odds for survival (Crude OR 14.1 95% CI (3.4-58.4), p < 0.001) and (Adjusted OR 12.3 95% CI (2.9 - 52.4), p < 0.001). Patient age beyond 66 years, further significantly decreased the odds for survival (Crude OR 36.1 95% CI (8.5-154.1), p < 0.001), and (Adjusted OR 26.6 95% CI (5.7 - 123.8), p < 0.001).
Conclusion: Our study indicates that older ages above 51 years and kidney disease increased mortality significantly in COVID-19 patients. Ethnicity was not significantly associated with mortality in the UAE population. Our findings are important in the management of the COVID-19 disease in the region with similar economic, social, cultural, and ethnic backgrounds.
(© 2021. The Author(s).)
Databáze: MEDLINE
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