Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) infections among undocumented migrants and uninsured legal residents in the Netherlands: A cross-sectional study, 2018-2019.

Autor: Klok S; NGO health care clinic Kruispost, Amsterdam, The Netherlands., van Dulm E; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands., Boyd A; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.; HIV Monitoring Foundation, Amsterdam, The Netherlands., Generaal E; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands., Eskander S; NGO health care clinic Kruispost, Amsterdam, The Netherlands., Joore IK; Department of Infectious Diseases, Public Health Service Flevoland, Lelystad, The Netherlands., van Cleef B; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands., Siedenburg E; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands., Bruisten S; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands., van Duijnhoven Y; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands., Tramper-Stranders G; NGO health care clinic Kruispost, Amsterdam, The Netherlands.; Department of Pediatrics, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands., Prins M; Department of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.; Division of Infectious Diseases, Department of Internal Medicine, Amsterdam UMC, Univ. of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity (AI&II), Amsterdam UMC, Univ. of Amsterdam, Amsterdam, the Netherlands.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2021 Oct 29; Vol. 16 (10), pp. e0258932. Date of Electronic Publication: 2021 Oct 29 (Print Publication: 2021).
DOI: 10.1371/journal.pone.0258932
Abstrakt: Background: Migrants are not routinely screened for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) in the Netherlands. We estimated the prevalence and determined factors associated with HBV, HCV and/or HIV infections among undocumented migrants and uninsured legal residents.
Methods: In this cross-sectional study, undocumented migrants and uninsured legal residents were recruited at a non governmental organization (NGO), healthcare facility in the Netherlands and were invited to be tested for hepatitis B surface antigen (HBsAg), anti-hepatitis B core antibodies (anti-HBcAb), HCV-RNA, and anti-HIV antibodies or HIV antigen at a local laboratory.
Results: Of the 1376 patients invited, 784 (57%) participated. Participants originated from Africa (35%), Asia (30%) and North/South America (30%). 451/784 (58%) participants went to the laboratory for testing. Of participants 30% were HBV exposed (anti-HBcAb-positive), with 27% (n = 119/438, 95% CI 23.1% to 31.6%) having resolved HBV infection (HBsAg-negative) and 2.5% (n = 11/438, 95%CI 1.3% to 4.5%, 64% new infection) having chronic HBV infection (HBsAg-positive). Compared to HBV non-exposed, HBV exposed individuals were older (p = 0.034) and more often originated from Africa (p<0.001). Prevalence of chronic HCV infection (HCV-RNA-positive) was 0.7% (n = 3/435, 95%CI 0.1% to 2.0%, all new infections) and HIV infection 1.1% (n = 5/439, 95%CI 0.04% to 2.6%, 40% new infection).
Conclusion: Prevalence of chronic HBV, chronic HCV and HIV infections in our study population is higher compared to the Dutch population, thus emphasizing the importance of case finding for these infections through primary care and public health in this specific group of migrants. Screening uptake could be improved by on-site testing.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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