Hafnium Oxide-Based Nanoplatform for Combined Chemoradiotherapy.
| Autor: | Sherstiuk AA; ITMO University, 9 Lomonosova, St. Petersburg 191002, Russia., Tsymbal SA; ITMO University, 9 Lomonosova, St. Petersburg 191002, Russia., Fakhardo AF; ITMO University, 9 Lomonosova, St. Petersburg 191002, Russia., Morozov VN; Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosigyna, Moscow 117334, Russia., Krivoshapkina EF; ITMO University, 9 Lomonosova, St. Petersburg 191002, Russia., Hey-Hawkins E; Leipzig University, Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Leipzig D-04103, Germany., Krivoshapkin PV; ITMO University, 9 Lomonosova, St. Petersburg 191002, Russia. |
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| Jazyk: | angličtina |
| Zdroj: | ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2021 Dec 13; Vol. 7 (12), pp. 5633-5641. Date of Electronic Publication: 2021 Oct 29. |
| DOI: | 10.1021/acsbiomaterials.1c00973 |
| Abstrakt: | Recently, the combined therapy has become one of the main approaches in cancer treatment. Combining different approaches may provide a significant outcome by triggering several death mechanisms or causing increased damage of tumor cells without hurting healthy ones. The supramolecular nanoplatform based on a high-Z metal reported here is a suitable system for the targeted delivery of chemotherapeutic compounds, imaging, and an enhanced radiotherapy outcome. HfO |
| Databáze: | MEDLINE |
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