Clinical efficacy of 0.75% ropivacaine vs. 2% lignocaine hydrochloride with adrenaline (1:80,000) in patients undergoing removal of bilateral maxillary third molars: a randomized controlled trial.

Autor:	Kakade AN; Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India., Joshi SS; Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India., Naik CS; Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India., Mhatre BV; Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India., Ansari A; Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India.
Jazyk:	angličtina
Zdroj:	Journal of dental anesthesia and pain medicine [J Dent Anesth Pain Med] 2021 Oct; Vol. 21 (5), pp. 451-459. Date of Electronic Publication: 2021 Oct 01.
DOI:	10.17245/jdapm.2021.21.5.451
Abstrakt:	Background: Lignocaine with adrenaline is routinely used as a local anesthetic for dental procedures. Adrenaline was added to increase the duration of anesthesia. However, epinephrine containing a local anesthetic solution is not recommended in conditions such as advanced cardiovascular diseases and hyperthyroidism. Recently, ropivacaine has gained popularity as a long-acting anesthetic with superior outcomes. The goal of this study was to assess and compare the effectiveness of 0.75% ropivacaine alone and 2% lignocaine with adrenaline (1:80,000) in the removal of bilateral maxillary wisdom teeth using the posterior superior alveolar nerve block technique. Methods: This was a single-blind, randomized, split-mouth, prospective study assessing 15 systemically sound outpatients who needed bilateral removal of maxillary third molars. We randomly allocated the sides and sequences of ropivacaine and lignocaine with adrenaline administration. We evaluated the efficacy of both anesthetics with regard to the onset of anesthesia, intensity of pain, variation in heart rate, and blood pressure. Results: The onset of anesthesia was faster with lignocaine (138 s) than with ropivacaine (168 s), with insignificant differences (p = 0.001). There was no need for additional local anesthetics in the ropivacaine group, while in the lignocaine with adrenaline group, 2 (13.3%) patients required additional anesthesia. Adequate intraoperative anesthesia was provided by ropivacaine and lignocaine solutions. No significant difference was observed in the perioperative variation in blood pressure and heart rate. Conclusion: Ropivacaine (0.75%) is a safe and an adrenaline-free local anesthetic option for posterior superior alveolar nerve block, which provides adequate intraoperative anesthesia and a stable hemodynamic profile for the removal of the maxillary third molar. Competing Interests: DECLARATION OF INTEREST: The authors have no conflicts of interest to declare. (Copyright © 2021 Journal of Dental Anesthesia and Pain Medicine.)
Databáze:	MEDLINE
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