A Biochemical Analysis of Patients with COVID-19 Infection.

Autor: Sarhan AR; Department of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, Iraq., Hussein TA; Department of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, Iraq., Flaih MH; Department of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, Iraq., Hussein KR; Department of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, Iraq.
Jazyk: angličtina
Zdroj: Biochemistry research international [Biochem Res Int] 2021 Oct 22; Vol. 2021, pp. 1383830. Date of Electronic Publication: 2021 Oct 22 (Print Publication: 2021).
DOI: 10.1155/2021/1383830
Abstrakt: Several studies have demonstrated that age, comorbidities, and abnormalities in different clinical biomarkers can be important to understand disease severity. Although clinical features of COVID-19 have been widely described, the assessment of alterations of the most common biochemical markers that are reported in patients with COVID-19 still has not been well established. Here, we report clinical and blood biochemical indicators of 100 patients with COVID-19. Throat-swab upper respiratory samples were obtained from patients and real-time PCR was used to confirm SARS-CoV-2 infection. Gender, age, and clinical features such as diabetes mellitus, hypertension, and smoking habits were investigated. Biochemical parameters were categorized and analyzed according to these clinical characteristics. Triglycerides, GPT, and ALP are the biochemical markers that changed the most in the group of hypertension patients. Cholesterol and triglycerides were significantly different ( P =0.01; P =0.04, respectively) between diabetic and nondiabetic patients with COVID-19. Potassium levels were significantly different ( P =0.03) when comparing smokers with nonsmoker patients. Our results suggest several potential biochemical indexes that changed in patients with COVID-19 and whether certain comorbidity and clinical characteristics influence these markers.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2021 Adil R. Sarhan et al.)
Databáze: MEDLINE
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